{"id":"W4401171429","doi":"10.3390/nano14151287","title":"Polyethylene Terephthalate Microplastics Generated from Disposable Water Bottles Induce Interferon Signaling Pathways in Mouse Lung Epithelial Cells","year":2024,"lang":"en","type":"article","venue":"Nanomaterials","topic":"Microplastics and Plastic Pollution","field":"Environmental Science","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Health Canada","funders":"Government of Canada","keywords":"Microplastics; Toxicity; Genotoxicity; Viability assay; Polyethylene terephthalate; Comet assay; In vivo; Cell; Chemistry; Biology; DNA damage; Materials science; Environmental chemistry; Biochemistry; DNA; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003732606,0.000316977,0.0003237705,0.00009929734,0.00009914629,0.000324763,0.0002333018,0.0002180531,0.005056344],"category_scores_gemma":[0.00002505642,0.000240021,0.00005995956,0.0001286119,0.00008706123,0.0002229224,0.0002547754,0.0001436442,0.001773834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002570304,"about_ca_system_score_gemma":0.00002677081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009825686,"about_ca_topic_score_gemma":0.00008388751,"domain_scores_codex":[0.9979078,0.0001485099,0.000580208,0.00058137,0.0002121591,0.0005699598],"domain_scores_gemma":[0.999446,0.0001317277,0.00006586232,0.000231728,0.000007802072,0.0001168577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009112831,0.00005408877,0.0003028522,0.00003153188,0.00002203177,0.0001006061,0.0007057442,0.001561817,0.9964892,0.0000160082,0.0003763355,0.0002486862],"study_design_scores_gemma":[0.0003047568,0.00006746893,0.0002500035,0.0001025479,0.00002862268,0.00001044151,0.00001895508,0.004810586,0.9926124,0.0001546413,0.001306978,0.000332587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994161,0.0001080946,0.001411198,0.00002531952,0.002510633,0.0002191789,0.001349934,0.0001041346,0.0001104994],"genre_scores_gemma":[0.9980493,0.00004556327,0.0008487651,0.00004224609,0.0002854472,0.00001626992,0.0001932178,0.00005352684,0.000465717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00388824,"threshold_uncertainty_score":0.9990034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01074270303358989,"score_gpt":0.203885122606566,"score_spread":0.1931424195729761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}