{"id":"W4401192414","doi":"10.1016/j.jbc.2024.107618","title":"Defining the functional properties of cyclopropane fatty acid synthase from Pseudomonas aeruginosa PAO1","year":2024,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; McGill University; University of Toronto; Massachusetts Institute of Technology","keywords":"Pseudomonas aeruginosa; Cyclopropane; Chemistry; ATP synthase; Biochemistry; Microbiology; Enzyme; Bacteria; Biology; Organic chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002938987,0.0001359835,0.0001962269,0.00001514809,0.00004079124,0.00002358001,0.0001724824,0.000175122,0.00005919732],"category_scores_gemma":[0.0002881756,0.00007122248,0.0001827323,0.0000805042,0.0001390003,0.000004872661,0.0000613442,0.0002544179,0.000002976609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000118105,"about_ca_system_score_gemma":0.00006738441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004822699,"about_ca_topic_score_gemma":2.084068e-7,"domain_scores_codex":[0.9991657,0.00003269424,0.0003485298,0.0001930225,0.0001276224,0.0001324781],"domain_scores_gemma":[0.9995378,0.0000128332,0.0001326969,0.0001577314,0.0001082401,0.00005066299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001397532,0.00004171403,0.0002438064,0.00005057155,0.0001101625,0.00000709849,0.00001799694,0.00008593264,0.996788,0.00001329382,0.0005210044,0.001980668],"study_design_scores_gemma":[0.0001342396,0.00008533977,0.0007057359,0.0001013678,0.000036958,0.0002416539,0.00006439483,0.00001776526,0.9884941,0.00002904129,0.009991254,0.00009813451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9710218,0.02710006,0.001001713,0.0003118551,0.0004068928,0.00003632942,0.000029658,0.0000112319,0.0000804051],"genre_scores_gemma":[0.997364,0.0007197092,0.0005262988,0.00003500584,0.001234464,0.000002809528,0.00003071108,0.00000861431,0.00007833491],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02638035,"threshold_uncertainty_score":0.2904368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01463487296086018,"score_gpt":0.212459426985845,"score_spread":0.1978245540249848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}