{"id":"W4401194967","doi":"10.3389/fimmu.2024.1434011","title":"Porcine γδ T cells express cytotoxic cell-associated markers and display killing activity but are not selectively cytotoxic against PRRSV- or swIAV-infected macrophages","year":2024,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Cytotoxic T cell; Granzyme B; Perforin; Granzyme; Biology; Interleukin 21; Immune system; Immunology; Cell biology; T cell; CD8; Molecular biology; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001307631,0.0003759814,0.0001929442,0.0001530284,0.0001162023,0.0003426407,0.0001385488,0.000413788,0.001947209],"category_scores_gemma":[0.0002009195,0.0001327105,0.0003792678,0.0001499206,0.000195591,0.0002681086,0.0002080324,0.000412967,0.0007357214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009839451,"about_ca_system_score_gemma":0.0001157577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002077226,"about_ca_topic_score_gemma":0.0001729275,"domain_scores_codex":[0.9998355,0.00001968413,0.0000234506,0.000050437,0.00002444787,0.00004647303],"domain_scores_gemma":[0.9998412,0.00004020659,0.00003468006,0.00003542721,0.00002526408,0.00002318902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000305622,0.00003727879,0.003858779,0.0001544268,0.00001499627,0.0002974828,0.0000675675,0.0001232986,0.9920374,0.00007232293,0.00007074445,0.002960053],"study_design_scores_gemma":[0.000123946,0.00401897,0.09562762,0.0001428531,0.0001762398,0.006887513,0.0005968413,0.00122925,0.8799542,0.0003695091,0.01083605,0.00003697514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929209,0.001744567,0.001546314,0.00004016865,0.00003433648,0.00003134977,0.000260935,0.00003102297,0.003390475],"genre_scores_gemma":[0.9957055,0.000668121,0.0008222725,0.00007390821,0.00001714921,0.00003403033,0.0008607416,0.000009832452,0.001808461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001947209,"threshold_uncertainty_score":0.006514013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007512131531145783,"score_gpt":0.2130994542597687,"score_spread":0.2055873227286229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}