{"id":"W4401198239","doi":"10.1016/j.cbpa.2024.111715","title":"Potency and specificity of amiloride and its analogues on branchial sodium fluxes in freshwater trout and goldfish","year":2024,"lang":"en","type":"article","venue":"Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; University of British Columbia","funders":"","keywords":"Amiloride; Potency; Sodium; Trout; Chemistry; Zoology; Biology; Fishery; Biochemistry; Fish <Actinopterygii>; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008066134,0.0002695038,0.0005820073,0.000385659,0.0002687236,0.0006992575,0.0004721624,0.0004840421,0.001642409],"category_scores_gemma":[0.001391821,0.0003829952,0.0004056099,0.0002288647,0.0008497884,0.0007828354,0.0004477075,0.0006872143,0.0003869389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000542545,"about_ca_system_score_gemma":0.0005316825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001997985,"about_ca_topic_score_gemma":0.0016362,"domain_scores_codex":[0.9995913,0.0001009643,0.00007052156,0.00007836682,0.00005810336,0.0001007273],"domain_scores_gemma":[0.9990114,0.0004746656,0.0001147637,0.00009520449,0.0001076586,0.0001962295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002345881,0.00002253859,0.0008536589,0.00007268667,0.00001795623,0.0000587355,0.00009652543,0.0001590845,0.9944515,0.0002569217,0.00002453181,0.001640077],"study_design_scores_gemma":[0.0001156626,0.002798896,0.026569,0.00001775635,0.00005966804,0.000227212,0.0002228823,0.0008986287,0.9678249,0.0001101887,0.001132117,0.00002297383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964377,0.0009557962,0.0004344437,0.00004362118,0.00001566774,0.00001531272,0.000113846,0.00001696093,0.001966701],"genre_scores_gemma":[0.9969682,0.0006371,0.0004714696,0.00005188426,0.00003085372,0.00002370759,0.0003105681,0.00002059971,0.001485544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001997985,"threshold_uncertainty_score":0.005494416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02157518002893227,"score_gpt":0.2589582097682559,"score_spread":0.2373830297393236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}