{"id":"W4401200560","doi":"10.1093/cid/ciae383","title":"A Phase 3 Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 in Pneumococcal Vaccine–Experienced Adults 50 Years of Age or Older (STRIDE-6)","year":2024,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Meso Scale Diagnostics","keywords":"Medicine; Immunogenicity; Tolerability; Pneumococcal conjugate vaccine; Serotype; Pneumococcal vaccine; Pneumococcal infections; Pneumococcal disease; Pediatrics; Streptococcus pneumoniae; Immunology; Internal medicine; Adverse effect; Antibody; Microbiology; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001872768,0.0009699604,0.001269138,0.0001987936,0.0003885557,0.00060363,0.0005875183,0.0009839124,0.003760482],"category_scores_gemma":[0.001062051,0.0003884037,0.001174125,0.000194212,0.0004863722,0.0004539144,0.0003590474,0.002017742,0.0006843455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004811734,"about_ca_system_score_gemma":0.001620044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006358281,"about_ca_topic_score_gemma":0.001417994,"domain_scores_codex":[0.9995947,0.0001925406,0.00002075203,0.00006555601,0.0000516399,0.00007478325],"domain_scores_gemma":[0.9990122,0.0001012217,0.0002574527,0.00008405973,0.0001065554,0.0004384403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7442754,0.1059376,0.01857549,0.0008128888,0.001316039,0.0002619946,0.0002733688,0.001438208,0.0500313,0.0002805717,0.003903526,0.07289366],"study_design_scores_gemma":[0.2948342,0.6793849,0.01958615,0.00003849187,0.0002735882,0.0002202983,0.00004547891,0.0006782576,0.002777289,0.0001390843,0.002005408,0.00001681012],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926036,0.0006877744,0.0006037017,0.000175655,0.0001060866,0.003839779,0.0008912187,0.00005307047,0.001039093],"genre_scores_gemma":[0.9849871,0.0009172847,0.002774652,0.0009802971,0.0001398581,0.005508702,0.00242936,0.0000222835,0.002240463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003760482,"threshold_uncertainty_score":0.0125801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05248748038116181,"score_gpt":0.4542837650786494,"score_spread":0.4017962846974876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}