{"id":"W4401200574","doi":"10.1093/neuonc/noae143","title":"Temozolomide use in elderly patients with MGMT promoter unmethylated glioblastoma: Is it finally time to dismount a dead horse?","year":2024,"lang":"en","type":"letter","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Temozolomide; Glioblastoma; Horse; Oncology; Medicine; Cancer research; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001370896,0.0008460255,0.001514719,0.001006123,0.00005906598,0.0001056282,0.0002746259,0.001328931,0.0007997145],"category_scores_gemma":[0.0002165407,0.000625334,0.0002555861,0.0007734769,0.0001184188,0.0001216467,0.0002169618,0.002259307,0.003997634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001054258,"about_ca_system_score_gemma":0.0005178732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001608768,"about_ca_topic_score_gemma":0.0003107836,"domain_scores_codex":[0.9957735,0.0003095024,0.0008083406,0.001467472,0.0006745101,0.0009666605],"domain_scores_gemma":[0.9977045,0.0006547266,0.0002621306,0.0008302709,0.0002699802,0.0002783755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001066988,0.001356273,0.007688664,0.0001895747,0.0004179379,0.03129521,0.0004709648,0.000004368586,0.001835443,9.0705e-7,0.9508077,0.004866007],"study_design_scores_gemma":[0.005548249,0.01958726,0.008405724,0.000614368,0.0009289919,0.0002429911,0.000007240847,0.00003258148,0.001246346,0.00001795485,0.9628204,0.0005479602],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.5621679,0.00005996154,9.831375e-7,0.4344904,0.0003382914,0.00221577,0.0001687936,0.00009673318,0.0004612087],"genre_scores_gemma":[0.06285708,0.00002804665,0.0005026578,0.9302491,0.0009322683,0.001283749,0.0007518998,0.0004168978,0.002978283],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.4993108,"threshold_uncertainty_score":0.9999676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01606540910877845,"score_gpt":0.270192571550423,"score_spread":0.2541271624416445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}