{"id":"W4401200574","doi":"10.1093/neuonc/noae143","title":"Temozolomide use in elderly patients with MGMT promoter unmethylated glioblastoma: Is it finally time to dismount a dead horse?","year":2024,"lang":"en","type":"letter","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Temozolomide; Glioblastoma; Horse; Oncology; Medicine; Cancer research; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005191138,0.0001229637,0.0005599342,0.0001666981,0.0001571373,0.0003012556,0.0002005241,0.0002559425,0.0003696846],"category_scores_gemma":[0.0008839138,0.00006569002,0.000357264,0.000386355,0.000158109,0.0004119297,0.0001259955,0.0004405542,0.0001036777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005320939,"about_ca_system_score_gemma":0.0004924144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001203211,"about_ca_topic_score_gemma":0.005367281,"domain_scores_codex":[0.999862,0.00004959588,0.00002240392,0.00001264746,0.00003478571,0.00001859338],"domain_scores_gemma":[0.9996697,0.00006265575,0.0001511918,0.000009011649,0.00003725886,0.00007016095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02336644,0.0006769025,0.257229,0.001946629,0.00104049,0.001247027,0.0003634594,0.000866672,0.009003449,0.0004036648,0.008084313,0.6957719],"study_design_scores_gemma":[0.003129867,0.02682631,0.8955337,0.001575953,0.002771293,0.004278941,0.0007921788,0.002023193,0.004723133,0.00135219,0.05690139,0.00009200523],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.8062798,0.186616,0.0003744776,0.00470864,0.000217802,0.00005631327,0.0002100865,0.00001834389,0.001518546],"genre_scores_gemma":[0.9508051,0.04499067,0.0004633594,0.002469023,0.0005605719,0.00003449135,0.0002914476,0.000004294555,0.0003810724],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.001203211,"threshold_uncertainty_score":0.003860593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01606540910877845,"score_gpt":0.270192571550423,"score_spread":0.2541271624416445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}