{"id":"W4401208157","doi":"10.1093/brain/awae181","title":"Clinical genetic testing in Parkinson’s disease should become part of routine patient care","year":2024,"lang":"en","type":"letter","venue":"Brain","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Aligning Science Across Parkinson’s; National Institutes of Health; Consortium canadien en neurodégénérescence associée au vieillissement; Michael J. Fox Foundation for Parkinson's Research","keywords":"Genetic testing; Parkinson's disease; Disease; Medicine; Psychiatry; Psychology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006543172,0.000874027,0.001679764,0.0009738847,0.004382114,0.003423145,0.002408305,0.08012278,0.0107176],"category_scores_gemma":[0.04578989,0.0007365479,0.002111099,0.001133864,0.003623178,0.006084693,0.001603375,0.05952876,0.01826394],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004666511,"about_ca_system_score_gemma":0.007666698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008201657,"about_ca_topic_score_gemma":0.01555345,"domain_scores_codex":[0.9927174,0.001993889,0.001224208,0.0008966785,0.002497513,0.0006703216],"domain_scores_gemma":[0.9711832,0.01634811,0.001201073,0.0009330375,0.006554705,0.003779863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002716866,0.00002652899,0.0003073454,0.00003898696,0.000006267943,0.0005401314,0.00004919331,0.00003051361,0.00009801058,0.001029744,0.9898903,0.007955686],"study_design_scores_gemma":[0.0001664444,0.0001059734,0.00188988,0.0008236405,0.00003152557,0.002445966,0.0003072442,0.000393921,0.0002349345,0.01485491,0.9786536,0.00009195229],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.00013823,0.0008975099,0.00005520704,0.9855716,0.0117075,0.000005896191,0.00004755197,0.00003055913,0.001546025],"genre_scores_gemma":[0.001115711,0.000842451,0.0001995365,0.9649363,0.03037146,0.00001759641,0.00003804813,0.00001820387,0.002460738],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.08012278,"threshold_uncertainty_score":0.03585392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06614527123710866,"score_gpt":0.3313307167632953,"score_spread":0.2651854455261867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}