{"id":"W4401209608","doi":"10.3390/biom14080922","title":"Complex Interplay between DNA Damage and Autophagy in Disease and Therapy","year":2024,"lang":"en","type":"review","venue":"Biomolecules","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Heart and Stroke Foundation of Canada","keywords":"Autophagy; DNA damage; Context (archaeology); Biology; DNA repair; Cancer; Disease; Cancer research; Programmed cell death; Bioinformatics; Medicine; DNA; Genetics; Apoptosis; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004186518,0.0005423416,0.001183276,0.00145466,0.0002857867,0.001018624,0.0005622217,0.0009597995,0.002569182],"category_scores_gemma":[0.0004918714,0.0001802377,0.0003966588,0.001235039,0.0004476034,0.0008445957,0.0006351773,0.001599895,0.001285506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000689263,"about_ca_system_score_gemma":0.001032491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007653593,"about_ca_topic_score_gemma":0.001850138,"domain_scores_codex":[0.9998053,0.00004154831,0.00002763507,0.00002544107,0.00008050878,0.0000196515],"domain_scores_gemma":[0.9998001,0.0000996227,0.00002190792,0.000006452359,0.00005221108,0.00001963666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000496903,0.00005335691,0.0001401716,0.01673774,0.0001009335,0.000201754,0.00009279502,0.000357762,0.002369215,0.007344794,0.03254216,0.9400096],"study_design_scores_gemma":[0.000009584087,0.00006836872,0.0005977244,0.003543162,0.00006372562,0.0009135263,0.00005102428,0.00007177907,0.0003854993,0.00256829,0.9917149,0.00001231361],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000104298,0.998334,0.0001001593,0.0003258948,0.0001493557,0.000003072895,0.00001147714,0.000007236749,0.0009644831],"genre_scores_gemma":[0.0006730493,0.9983906,0.0001341015,0.0001730686,0.0001086081,0.000005144507,0.00001665999,0.000001174116,0.0004977486],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002569182,"threshold_uncertainty_score":0.008594751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06731449873720582,"score_gpt":0.4105171082510598,"score_spread":0.343202609513854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}