{"id":"W4401214740","doi":"10.1089/derm.2024.0084","title":"An Open-Label Prospective Observational Study of Tralokinumab in Atopic Dermatitis Patients with Inadequate Response to Dupilumab","year":2024,"lang":"en","type":"letter","venue":"Dermatitis","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Dupilumab; Medicine; Atopic dermatitis; Observational study; Dermatology; Open label; Randomized controlled trial; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002378994,0.0004746397,0.001149376,0.0003601259,0.0007693773,0.001472283,0.000629945,0.001667538,0.001405818],"category_scores_gemma":[0.006934992,0.0005041127,0.001194758,0.0008481999,0.0005160469,0.001160027,0.000333004,0.002032376,0.0003516754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001049139,"about_ca_system_score_gemma":0.0008129466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004022582,"about_ca_topic_score_gemma":0.004503685,"domain_scores_codex":[0.9975782,0.00108484,0.0002856012,0.0005042284,0.0002783031,0.0002688528],"domain_scores_gemma":[0.9919533,0.003503478,0.002260519,0.0006300297,0.0006973543,0.0009553896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01780841,0.001112186,0.9719572,0.00008309975,0.000720842,0.002273416,0.0002252148,0.00004613633,0.00098772,0.00005921938,0.001098535,0.003628014],"study_design_scores_gemma":[0.003596902,0.006282754,0.9816553,0.00004368099,0.0008933593,0.004035578,0.0005591279,0.00110261,0.0001822065,0.0001617588,0.001437248,0.00004945472],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979626,0.0004456151,0.0001137929,0.0006068432,0.00009330338,0.00003392328,0.0003679717,0.000004238701,0.0003717812],"genre_scores_gemma":[0.9977464,0.0001341819,0.0001173496,0.001236813,0.0001678577,0.00002997832,0.0002946699,0.000002628874,0.0002701636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004022582,"threshold_uncertainty_score":0.01258153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03999547462722711,"score_gpt":0.313750229055454,"score_spread":0.2737547544282269,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}