{"id":"W4401218979","doi":"10.3899/jrheum.2024-0444","title":"Cell Composition Analysis of Matched Salivary Organoid and Adherent Cultures: Choose Your Sjögren Disease Research Tool Carefully","year":2024,"lang":"en","type":"letter","venue":"The Journal of Rheumatology","topic":"Salivary Gland Disorders and Functions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Lymphocytic infiltration; Salivary gland; Infiltration (HVAC); Organoid; Pathology; Disease; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007051963,0.0002517205,0.001139209,0.001030456,0.0001293434,0.00003213836,0.0002522442,0.0003819642,0.0004024548],"category_scores_gemma":[0.0001038608,0.0001447391,0.000401817,0.0007676563,0.0002794565,0.00005231713,0.0001169974,0.002081835,0.00002315649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007364309,"about_ca_system_score_gemma":0.0003638159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003139398,"about_ca_topic_score_gemma":0.00001341643,"domain_scores_codex":[0.9974251,0.0005551629,0.0008312693,0.000219634,0.0006526381,0.0003161603],"domain_scores_gemma":[0.9978845,0.0004997941,0.0004642955,0.0004339664,0.000573138,0.0001443737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001268435,0.0001868283,0.03868208,0.001207566,0.003499667,0.000389949,0.001641082,0.00002795104,0.0002532156,0.00003588125,0.9527153,0.00009206234],"study_design_scores_gemma":[0.02186781,0.007522448,0.235133,0.01029298,0.194361,0.02961205,0.02202592,0.002194127,0.0005926732,0.01232938,0.4610566,0.003011979],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7440438,0.01945222,0.0001200422,0.2349261,0.000542767,0.0003734911,0.0001652037,0.00002006609,0.0003562643],"genre_scores_gemma":[0.9583027,0.01056062,0.0001363671,0.02821214,0.0003445645,0.00001410287,0.0006332504,0.00008118033,0.001715025],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4916587,"threshold_uncertainty_score":0.9044654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03462917603124151,"score_gpt":0.3287737831892065,"score_spread":0.294144607157965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}