{"id":"W4401232426","doi":"10.1136/annrheumdis-2024-eular.1873","title":"AB0459 BASELINE (BL) DEMOGRAPHICS AND DISEASE CHARACTERISTICS BY MENOPAUSAL STATUS AND SEX IN PATIENTS FROM A PHASE 2 TRIAL OF DEUCRAVACITINIB, A FIRST-IN-CLASS, ORAL, SELECTIVE, ALLOSTERIC TYROSINE KINASE 2 INHIBITOR, IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS (PsA)","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Microscopic Colitis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women's College Hospital; University of Toronto","funders":"","keywords":"Demographics; Internal medicine; Medicine; Disease; Kinase; Class (philosophy); Allosteric regulation; Pharmacology; Oncology; Biology; Genetics; Computer science; Demography; Receptor; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003401473,0.000277756,0.0006428807,0.0002404656,0.0003300152,0.0003958806,0.0001590373,0.0004010194,0.004386929],"category_scores_gemma":[0.0006514917,0.0001720333,0.0005598278,0.0002581772,0.0001574472,0.0004254703,0.0001463837,0.0006674376,0.0005283285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002354919,"about_ca_system_score_gemma":0.0003320058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001363822,"about_ca_topic_score_gemma":0.002627156,"domain_scores_codex":[0.9997675,0.00004000032,0.00002065873,0.00007083775,0.00003077795,0.00007028179],"domain_scores_gemma":[0.9996895,0.00007280688,0.00006370777,0.00001618325,0.00001959671,0.000138323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2342703,0.004869673,0.6518478,0.000290626,0.001717507,0.001124828,0.0002257521,0.001563142,0.02046609,0.0002204925,0.009953972,0.07344986],"study_design_scores_gemma":[0.009765746,0.02382216,0.9583778,0.00002796693,0.0005419093,0.0008700903,0.0001387888,0.000878174,0.0008833936,0.0002190103,0.00444731,0.00002766328],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938523,0.0008974026,0.0001115657,0.0001268352,0.00004553616,0.00007350477,0.002871847,0.00001425578,0.002006824],"genre_scores_gemma":[0.9953206,0.0002229234,0.00008424873,0.00028648,0.00004408005,0.00007508961,0.003039959,0.00000425446,0.0009222938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004386929,"threshold_uncertainty_score":0.01467574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0107916210022197,"score_gpt":0.2683150582866748,"score_spread":0.2575234372844551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}