{"id":"W4401284543","doi":"10.1016/j.yexcr.2024.114198","title":"Macrophage-based cancer immunotherapy: Challenges and opportunities","year":2024,"lang":"en","type":"review","venue":"Experimental Cell Research","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University","funders":"","keywords":"Tumor microenvironment; Immunotherapy; Biology; Cancer immunotherapy; Macrophage; Adoptive cell transfer; Immune system; Crosstalk; Metastasis; Cancer; Immunology; Cancer research; Tumor-associated macrophage; T cell; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001738529,0.001222434,0.001995686,0.001984851,0.000351091,0.001963105,0.001316273,0.002227605,0.003854104],"category_scores_gemma":[0.001404247,0.0003465669,0.0005143692,0.001970689,0.00116426,0.002423862,0.001289909,0.004415686,0.002621362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001115805,"about_ca_system_score_gemma":0.001652569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009747734,"about_ca_topic_score_gemma":0.00252536,"domain_scores_codex":[0.9996862,0.00007894679,0.00002570996,0.00004290912,0.0001193354,0.000046916],"domain_scores_gemma":[0.9993387,0.0003447612,0.00004841333,0.00001960311,0.0001560895,0.00009255212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001708688,0.0001111206,0.0001158385,0.009772884,0.00005712444,0.0001233917,0.00004748111,0.0004814902,0.002086477,0.01051432,0.1012332,0.8752858],"study_design_scores_gemma":[0.0000344365,0.000082099,0.0002154304,0.002190701,0.00004270612,0.0003094872,0.00003830273,0.00009909387,0.0002460069,0.003153349,0.9935753,0.00001313164],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003029432,0.9981242,0.0001161392,0.0006050995,0.0005621026,0.0000025953,0.000008517138,0.000005215088,0.000545849],"genre_scores_gemma":[0.0002933815,0.997817,0.000172631,0.0004902509,0.0007056773,0.000006762518,0.00001965247,0.000001519041,0.0004930962],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003854104,"threshold_uncertainty_score":0.01289326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3267870930380513,"score_gpt":0.4691309753759763,"score_spread":0.1423438823379251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}