{"id":"W4401373595","doi":"10.1152/ajpgi.00049.2023","title":"Decreased Expression of DRA (SLC26A3) by a p38 Driven IL-1α Response Contributes to Diarrheal Disease Following In vivo Challenge with Brachyspira spp.","year":2024,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Veterinary medicine and infectious diseases","field":"Veterinary","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Livestock and Meat Agency","keywords":"Diarrheal disease; Diarrheal diseases; In vivo; Biology; Diarrhea; Disease; Microbiology; Medicine; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002095088,0.0004265041,0.0002904421,0.000180472,0.0001630943,0.00025365,0.0001705557,0.0003733186,0.001195363],"category_scores_gemma":[0.0001102337,0.0001823687,0.0004296842,0.00008424511,0.0002655332,0.0002201011,0.0002106717,0.0007921374,0.000364337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001863999,"about_ca_system_score_gemma":0.0001607842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002971893,"about_ca_topic_score_gemma":0.0005775344,"domain_scores_codex":[0.9997997,0.00003631246,0.00001584854,0.00004530032,0.00004699441,0.00005588191],"domain_scores_gemma":[0.999871,0.00001165323,0.0000519384,0.00001240435,0.00001941898,0.00003352336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008482738,0.00001130029,0.000190949,0.00002367514,0.000002170465,0.00003561956,0.000008959476,0.000007040841,0.9994491,0.00000585921,0.000008884701,0.0001717438],"study_design_scores_gemma":[0.00002037277,0.001351381,0.03544113,0.00001333531,0.00003205641,0.0007965386,0.000163412,0.0008020066,0.9592838,0.00005606118,0.002030081,0.000009878368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951108,0.001201707,0.002146998,0.000204306,0.00003979693,0.0000455108,0.0004230793,0.00006208244,0.0007658591],"genre_scores_gemma":[0.9941328,0.0006942978,0.002654844,0.0001062786,0.0000220871,0.00005538497,0.0005333547,0.00001433183,0.001786698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001195363,"threshold_uncertainty_score":0.003998935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01288320611411807,"score_gpt":0.2757003549417221,"score_spread":0.262817148827604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}