{"id":"W4401374482","doi":"10.1007/978-1-0716-3995-5_15","title":"Isolation and Characterization of Extracellular Vesicles from Cell Culture Media","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"","keywords":"Isolation (microbiology); Extracellular vesicles; Characterization (materials science); Vesicle; Cell biology; Chemistry; Biology; Microbiology; Materials science; Nanotechnology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006285141,0.000728881,0.0006891566,0.0006595222,0.0006355664,0.001365609,0.0006600711,0.0004900122,0.0007935888],"category_scores_gemma":[0.000858426,0.0002578377,0.0006021908,0.0006015443,0.0003235413,0.0006065793,0.0007846334,0.001163452,0.001033337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003812388,"about_ca_system_score_gemma":0.0004705106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008758144,"about_ca_topic_score_gemma":0.00113559,"domain_scores_codex":[0.9995121,0.00007002924,0.00009122799,0.00007738567,0.0001574075,0.00009188223],"domain_scores_gemma":[0.9995785,0.0001341699,0.00004192984,0.00008250979,0.0001136975,0.00004914969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000550694,0.00002062375,0.0001247049,0.00005350005,0.000007156814,0.00006692413,0.00003646269,0.00006966645,0.997203,0.000308834,0.00004953243,0.002004605],"study_design_scores_gemma":[0.00001369238,0.00005944567,0.001882184,0.0000269538,0.00002255083,0.000227332,0.00003659897,0.0007834031,0.9890955,0.0001939343,0.007650334,0.000008039719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.7253214,0.01347846,0.2349475,0.0008742351,0.0005233876,0.002346123,0.009728436,0.0005496853,0.01223082],"genre_scores_gemma":[0.7628184,0.01109365,0.175063,0.0003808846,0.0001551077,0.002198979,0.02818514,0.0006108159,0.01949402],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001365609,"threshold_uncertainty_score":0.003323972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01059991900540288,"score_gpt":0.3169233102783051,"score_spread":0.3063233912729022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}