{"id":"W4401378486","doi":"10.1016/j.jcmgh.2024.101387","title":"Acvr1b Loss Increases Formation of Pancreatic Precancerous Lesions From Acinar and Ductal Cells of Origin","year":2024,"lang":"en","type":"article","venue":"Cellular and Molecular Gastroenterology and Hepatology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health; Michael Smith Health Research BC","keywords":"Pathology; Pancreatic carcinoma; Medicine; Internal medicine; Pancreatic cancer; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002243201,0.0004131341,0.000345997,0.0005601742,0.0001994395,0.0006478452,0.0003733503,0.0006877981,0.003880928],"category_scores_gemma":[0.0002335982,0.0003686576,0.0003834029,0.0002365999,0.0003551011,0.0003488812,0.0003061584,0.001030372,0.0008485884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003966387,"about_ca_system_score_gemma":0.0002472732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007328127,"about_ca_topic_score_gemma":0.0009324845,"domain_scores_codex":[0.9995739,0.00006253651,0.00005911196,0.0001037674,0.0001156401,0.00008507723],"domain_scores_gemma":[0.9995473,0.0000577834,0.0001769636,0.0000451078,0.00003066279,0.0001421807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002080032,0.00004564481,0.0004387547,0.00004929989,0.000009330923,0.00005457719,0.00001884807,0.00003629596,0.9983749,0.00005820625,0.00004560803,0.0006604495],"study_design_scores_gemma":[0.00004413688,0.0005741348,0.01152974,0.00001732711,0.00004263935,0.0009435081,0.00007420118,0.0006369165,0.9830878,0.00004024661,0.003001764,0.000007533235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936127,0.002749599,0.001437886,0.0001401145,0.00003293692,0.00002451586,0.0005138599,0.0002036343,0.001284725],"genre_scores_gemma":[0.9941466,0.001051031,0.001273349,0.00004897279,0.00001026138,0.00003309351,0.0006832189,0.0000509015,0.00270242],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003880928,"threshold_uncertainty_score":0.01298296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01465183634482601,"score_gpt":0.2832297506576134,"score_spread":0.2685779143127874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}