{"id":"W4401385902","doi":"10.1016/j.ajt.2024.07.034","title":"Subthreshold rejection activity in many kidney transplants currently classified as having no rejection","year":2024,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Paul's Hospital; The Metabolomics Innovation Centre; University of Alberta","funders":"Ministry of Advanced Education; University of Alberta; Natera; Mendez National Institute of Transplantation Foundation; Genome Canada","keywords":"Medicine; Graft rejection; Kidney transplant; Kidney transplantation; Kidney; Subthreshold conduction; Transplanted kidney; Intensive care medicine; Internal medicine; Transplantation; Electrical engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004199668,0.0001289584,0.0002642038,0.0007534806,0.0003246333,0.0007232288,0.0001849797,0.000234568,0.002095748],"category_scores_gemma":[0.001879166,0.00007192327,0.0003152701,0.0008335023,0.0002656094,0.0004293372,0.0003050969,0.0005592489,0.0002259108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001751183,"about_ca_system_score_gemma":0.0003229229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001432774,"about_ca_topic_score_gemma":0.002758935,"domain_scores_codex":[0.9997062,0.00006217364,0.00004441231,0.00003582317,0.0000778352,0.00007346526],"domain_scores_gemma":[0.9984469,0.000239578,0.0008216316,0.00006478263,0.000114908,0.0003123235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002140839,0.0000288087,0.9951302,0.0000130653,0.00001503167,0.0001963104,0.00004652104,0.00002362266,0.0007789549,0.00005798384,0.00005082525,0.003444602],"study_design_scores_gemma":[0.000002691282,0.00007305649,0.9982345,0.000008205681,0.00001854106,0.0009416527,0.0001518147,0.00006473964,0.0001764047,0.00009531743,0.0002303658,0.000002556255],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972365,0.0006106276,0.0001061993,0.0001092778,0.00001998974,0.000004760303,0.00009227881,0.00000320732,0.001817031],"genre_scores_gemma":[0.9995331,0.0001422343,0.00004142701,0.00003299821,0.00002106826,0.000001155003,0.00008604678,0.000001091451,0.0001409596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002095748,"threshold_uncertainty_score":0.007010996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01956836615225838,"score_gpt":0.3152720253955656,"score_spread":0.2957036592433073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}