{"id":"W4401391503","doi":"10.7554/elife.97827.1.sa3","title":"eLife Assessment: CPT1A Mediates Radiation Sensitivity in Colorectal Cancer","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Radioresistance; Radiosensitivity; Biology; Cancer research; Radiation therapy; Colorectal cancer; Transcriptome; Downregulation and upregulation; Radiation sensitivity; Cancer; Medicine; Internal medicine; Genetics; Gene expression; Gene; Irradiation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0005185344,0.0004143598,0.0004739598,0.0008864673,0.0008059607,0.001250817,0.0006854515,0.0009857255,0.02255503],"category_scores_gemma":[0.0009893676,0.0003519811,0.0003745647,0.000797178,0.0004941801,0.0006618387,0.001029454,0.001516879,0.006752053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001062078,"about_ca_system_score_gemma":0.001323763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002122261,"about_ca_topic_score_gemma":0.004141006,"domain_scores_codex":[0.9993949,0.00004698152,0.00002595804,0.0001492651,0.0003016604,0.00008121272],"domain_scores_gemma":[0.9996018,0.00005619687,0.00008140821,0.00002721471,0.0001511492,0.00008233813],"domain_codex":null,"domain_gemma":"evaluation","domain_candidate":"evaluation","domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001760846,0.0001555446,0.01761796,0.003139938,0.0002507146,0.001504257,0.0003694533,0.002435343,0.6338394,0.01163566,0.1234473,0.2038437],"study_design_scores_gemma":[0.0002385655,0.0003788913,0.04851797,0.0004377709,0.0002479761,0.002685078,0.0006141497,0.01148536,0.3488935,0.007124359,0.5792871,0.00008933358],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.4456058,0.08977047,0.1437457,0.04345088,0.008010835,0.0006729681,0.05878426,0.01375116,0.196208],"genre_scores_gemma":[0.7471455,0.03010262,0.0506161,0.006887192,0.001102366,0.0005597587,0.02895623,0.001125635,0.1335045],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.9994814,"threshold_uncertainty_score":0.07545406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01138653314246151,"score_gpt":0.3214849285017243,"score_spread":0.3100983953592628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}