{"id":"W4401414353","doi":"10.1126/science.adq9566","title":"Locking away depression","year":2024,"lang":"en","type":"letter","venue":"Science","topic":"Treatment of Major Depression","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Depression (economics); Antidepressant; Ketamine; Neuroscience; Psychology; Medicine; Psychiatry; Hippocampus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001864363,0.0008607293,0.0008932239,0.0004726927,0.002492437,0.002174925,0.001011249,0.02403181,0.005239764],"category_scores_gemma":[0.01462673,0.0003966589,0.0009139216,0.0002575026,0.002139892,0.00324487,0.001088228,0.02854037,0.005927112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003232222,"about_ca_system_score_gemma":0.001920506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00358657,"about_ca_topic_score_gemma":0.005190501,"domain_scores_codex":[0.9985029,0.0005166411,0.000152506,0.0001871786,0.0004604796,0.000180378],"domain_scores_gemma":[0.9971212,0.001639204,0.0001477043,0.0001275271,0.0004952155,0.0004691567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001276663,0.00005416483,0.0004142277,0.00006526662,0.00002075543,0.002236121,0.0001035898,0.00005520116,0.0004858048,0.004211865,0.96546,0.02676523],"study_design_scores_gemma":[0.0004502733,0.0002805814,0.001672279,0.0005012453,0.00004811612,0.007158955,0.0004671398,0.0008472881,0.0005716588,0.02711838,0.9608146,0.00006961454],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0004779107,0.003688195,0.0001561279,0.9672393,0.02449295,0.00001717064,0.00003003886,0.00003121802,0.003867046],"genre_scores_gemma":[0.006782627,0.003651681,0.0003349803,0.9248002,0.05282144,0.00005009145,0.00002228806,0.00002291649,0.01151374],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02403181,"threshold_uncertainty_score":0.02345157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02334411227446422,"score_gpt":0.3158174661924198,"score_spread":0.2924733539179556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}