{"id":"W4401422101","doi":"10.1002/alz.14182","title":"Clonal hematopoiesis of indeterminate potential is associated with reduced risk of cognitive impairment in patients with chronic kidney disease","year":2024,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institute on Aging; Clinical and Translational Science Collaborative of Cleveland, School of Medicine, Case Western Reserve University; Michigan Institute for Clinical and Health Research; University of California, San Francisco; University of Illinois at Urbana-Champaign; National Institutes of Health; National Center for Research Resources; University of Pennsylvania; Georgia Clinical and Translational Science Alliance; National Institute of Diabetes and Digestive and Kidney Diseases; Johns Hopkins University; Kaiser Permanente; Deutsches Krebsforschungszentrum; Perelman School of Medicine, University of Pennsylvania; U.S. Department of Veterans Affairs","keywords":"Indeterminate; Cognitive impairment; Disease; Kidney disease; Medicine; Cognition; Internal medicine; Immunology; Oncology; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006396265,0.0002095907,0.0002758871,0.000515305,0.0002812736,0.0005159675,0.0002529368,0.0003355001,0.001084316],"category_scores_gemma":[0.00274365,0.0001477271,0.0003340588,0.0005454004,0.000244699,0.0002422204,0.0003322164,0.0004046627,0.00006654172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001860082,"about_ca_system_score_gemma":0.0002352782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002856971,"about_ca_topic_score_gemma":0.003228894,"domain_scores_codex":[0.9997675,0.00007269626,0.00001981799,0.00005431257,0.0000447336,0.00004106967],"domain_scores_gemma":[0.9984946,0.0003264886,0.0007767829,0.0001091717,0.0001195708,0.0001732941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003772664,0.00002071092,0.9970632,0.00001071654,0.0000737455,0.00005584877,0.00002522853,0.0000501724,0.0003576552,0.00001470832,0.00005274918,0.001897897],"study_design_scores_gemma":[0.000007233757,0.00006514964,0.9993936,0.000003580102,0.00004153132,0.0001302683,0.00001871722,0.0001635879,0.00007144856,0.00003516267,0.00006780386,0.000001949206],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992881,0.0003205128,0.00007756041,0.00002804688,0.000002646495,0.000002496061,0.0001028728,0.000002743471,0.0001750319],"genre_scores_gemma":[0.9997292,0.00005447524,0.00004931933,0.00001540556,0.00000592463,0.000001701868,0.00008097273,6.761182e-7,0.00006230517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002856971,"threshold_uncertainty_score":0.00568068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009264431213869075,"score_gpt":0.2631599688524462,"score_spread":0.2538955376385771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}