{"id":"W4401422375","doi":"10.1001/jama.2024.11437","title":"Oral Antibiotics and Risk of Serious Cutaneous Adverse Drug Reactions","year":2024,"lang":"en","type":"article","venue":"JAMA","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Clinical Evaluative Sciences; St. Michael's Hospital; Women's College Hospital; University of Toronto","funders":"","keywords":"Medicine; Antibiotics; Drug reaction; Drug; Dermatology; Adverse drug reaction; Skin reaction; Adverse effect; Relative risk; Intensive care medicine; Pharmacology; Internal medicine; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001039884,0.0001074343,0.0001946659,0.0001564317,0.00005693961,0.00001767352,0.00003174625,0.00008520835,0.00002323142],"category_scores_gemma":[0.0001955607,0.00009451566,0.00008523761,0.0002581301,0.00008135068,0.0001285177,0.00002963878,0.000358852,0.0001130579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007109498,"about_ca_system_score_gemma":0.00009066911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005195198,"about_ca_topic_score_gemma":0.00008295511,"domain_scores_codex":[0.9992688,0.00002687585,0.0001981481,0.0002010556,0.0001551305,0.0001499803],"domain_scores_gemma":[0.9994005,0.0001151391,0.00005465668,0.0002398367,0.00007000055,0.0001198992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001094781,0.0007044558,0.02270923,0.001510389,0.001678923,0.003653047,0.003025664,0.0001791808,0.1024598,0.004064252,0.007554558,0.852351],"study_design_scores_gemma":[0.002546381,0.0001548653,0.1182987,0.001094174,0.002450736,0.009476104,0.003429581,0.009351343,0.02430621,0.0005771573,0.8278435,0.0004713111],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.967042,0.000217936,0.00004672947,0.001036453,0.000652081,0.000217132,0.00007358361,0.0001882505,0.03052579],"genre_scores_gemma":[0.9912665,0.0009158216,0.001089483,0.00004622073,0.0001665578,4.478875e-7,0.00001356333,0.00002697023,0.006474364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8518797,"threshold_uncertainty_score":0.3854237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01063356060909184,"score_gpt":0.2729686405660766,"score_spread":0.2623350799569847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}