{"id":"W4401432910","doi":"10.1016/j.transci.2024.103987","title":"Towards personalized and rational use of immunoglobulins amid expanding indications and shortages","year":2024,"lang":"en","type":"review","venue":"Transfusion and Apheresis Science","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Economic shortage; Medicine; Context (archaeology); Immunology; Transplantation; Antibody; Lymphoma; Intensive care medicine; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004433593,0.00030064,0.0007300752,0.0003480221,0.0006477559,0.0001255166,0.0002331923,0.0002351978,0.0001822003],"category_scores_gemma":[0.00007029086,0.0002200518,0.0001392739,0.0005991794,0.002702908,0.000257445,0.0001300128,0.0003290656,0.000009825973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001869679,"about_ca_system_score_gemma":0.0003243892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001593147,"about_ca_topic_score_gemma":0.000007556232,"domain_scores_codex":[0.9984581,0.0001150458,0.0004778024,0.000567467,0.0001061447,0.0002753905],"domain_scores_gemma":[0.999439,0.000157046,0.0001332692,0.0002007406,0.00005037813,0.00001955097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002184759,0.00007647236,0.00002956346,0.00244908,0.0001187122,0.000001789568,0.002047313,1.263765e-7,0.01380549,0.007767277,0.000042809,0.9736395],"study_design_scores_gemma":[0.0008456028,0.0001694343,0.001833158,0.007766678,0.001431446,0.0002459396,0.001932904,0.0000150651,0.0006483594,0.0002480296,0.9840648,0.0007986269],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01835169,0.9805384,0.00008648704,0.00006331399,0.0002188331,0.0003759672,0.0001299132,0.00003467452,0.0002007039],"genre_scores_gemma":[0.03156822,0.9675748,0.00007045872,0.000020205,0.00000232372,0.00002908132,0.00005317813,0.00001461251,0.0006671704],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.984022,"threshold_uncertainty_score":0.9958977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04992199204491402,"score_gpt":0.3308995854700633,"score_spread":0.2809775934251493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}