{"id":"W4401443721","doi":"10.22541/au.172320180.09605335/v1","title":"Female Oncofertility and Immune Checkpoint Blockade in Melanoma: Where Are We Today?","year":2024,"lang":"en","type":"preprint","venue":"","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Princess Margaret Cancer Foundation","keywords":"Medicine; Pregnancy; Melanoma; Fertility preservation; Disease; Oncofertility; Fertility; Oncology; Cancer; Immunotherapy; Immune checkpoint; Gynecology; Immunology; Internal medicine; Population; Cancer research; Environmental health; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001802431,0.0002808676,0.0006500967,0.0004647674,0.0004698069,0.001950388,0.0002461298,0.001213492,0.01061728],"category_scores_gemma":[0.003536666,0.000137876,0.0003689159,0.0005301014,0.0008090659,0.001745664,0.0005694094,0.001875551,0.002515445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007704951,"about_ca_system_score_gemma":0.001508482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001264623,"about_ca_topic_score_gemma":0.002019933,"domain_scores_codex":[0.9996535,0.0001479989,0.00001991865,0.00003456074,0.00009326541,0.00005082018],"domain_scores_gemma":[0.9990101,0.0004001535,0.0001302656,0.00007658199,0.0001659656,0.0002169038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001196815,0.0001955898,0.01225289,0.00115512,0.0001453865,0.00123892,0.0002426911,0.0002205532,0.001972369,0.01465714,0.2119549,0.7547677],"study_design_scores_gemma":[0.0001728452,0.0005575203,0.03797178,0.002384639,0.0002048805,0.005713719,0.001165521,0.0003574591,0.001842,0.04561945,0.9039457,0.0000644121],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01920689,0.6056557,0.00176531,0.3301736,0.01328966,0.00002583315,0.0005280675,0.0001789912,0.02917584],"genre_scores_gemma":[0.2167723,0.6654371,0.00278607,0.0373281,0.03767531,0.00007423132,0.0005540818,0.0001700422,0.0392027],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01061728,"threshold_uncertainty_score":0.03551835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01104351208095165,"score_gpt":0.2540003889902074,"score_spread":0.2429568769092557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}