{"id":"W4401443933","doi":"10.1111/aji.13908","title":"Maternal Innate Immune Reprogramming After Complicated Pregnancy","year":2024,"lang":"en","type":"article","venue":"American Journal of Reproductive Immunology","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine; Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Immunology; Monocyte; H3K4me3; Immune system; Inflammation; Innate immune system; Biology; Population; Cytokine; Reprogramming; Epigenetics; Preeclampsia; Tumor necrosis factor alpha; Pregnancy; Endocrinology; Internal medicine; Medicine; Cell; Gene expression; Gene; Genetics; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001054225,0.000430444,0.001096995,0.0006060756,0.0001434882,0.00007181489,0.0006349221,0.0001732677,0.0003673644],"category_scores_gemma":[0.0003005369,0.0003405469,0.0004418202,0.0008874647,0.001750292,0.0004540219,0.0002083368,0.001109262,0.0006211792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001471762,"about_ca_system_score_gemma":0.0001901883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002337727,"about_ca_topic_score_gemma":0.000002062074,"domain_scores_codex":[0.9958952,0.0009028596,0.001337212,0.0010581,0.0001140515,0.0006925799],"domain_scores_gemma":[0.9969467,0.0001726621,0.0009481679,0.001191962,0.0006976457,0.0000428992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001229593,0.0002370264,0.02255417,0.0001171152,0.003863688,0.0007229163,0.002998578,0.000007544324,0.5492405,0.001174178,0.000329399,0.4175253],"study_design_scores_gemma":[0.002142048,0.006638185,0.3712488,0.004563337,0.0006113594,0.04093913,0.002833333,0.000001459571,0.4452011,0.002856089,0.121642,0.001323128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6894739,0.3024708,0.0007551163,0.001232157,0.004929359,0.0003636928,0.00001641319,0.0001529802,0.0006055479],"genre_scores_gemma":[0.9957467,0.0009359231,0.0006016333,0.00002967005,0.000330415,0.00006404232,0.00001160217,0.00007252765,0.00220753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4162022,"threshold_uncertainty_score":0.9999046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008095510195532016,"score_gpt":0.2506437325897417,"score_spread":0.2425482223942096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}