{"id":"W4401493903","doi":"10.1038/s42003-024-06675-8","title":"Platelet extracellular vesicles preserve lymphatic endothelial cell integrity and enhance lymphatic vessel function","year":2024,"lang":"en","type":"article","venue":"Communications Biology","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"HEC Montréal; Centre hospitalier de l'Université Laval; McGill University; Montreal Heart Institute; Centre hospitalier universitaire de Québec; McGill University Health Centre; Université Laval; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; Heart and Stroke Foundation of Canada","keywords":"Lymphatic system; Lymphatic Endothelium; Extracellular vesicles; Cell biology; Platelet; Function (biology); Endothelial stem cell; Extracellular; Chemistry; Vesicle; Lymphatic vessel; Endothelium; Pathology; Medicine; Immunology; Biology; Biochemistry; Membrane; In vitro; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000309167,0.0001731197,0.0002936857,0.0001396233,0.0001707112,0.00005726184,0.0003121119,0.0001535293,0.0000795392],"category_scores_gemma":[0.0002020132,0.0001407962,0.00008368758,0.0002086637,0.0003453674,0.0001266888,0.0002051981,0.00006379694,0.0002230328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008839966,"about_ca_system_score_gemma":0.0002746959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009075293,"about_ca_topic_score_gemma":0.00001139444,"domain_scores_codex":[0.9987081,0.000299272,0.0003798908,0.000311375,0.00008779545,0.0002135091],"domain_scores_gemma":[0.9977509,0.0007631555,0.00007607356,0.001195678,0.00008066708,0.0001334946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007984281,0.002884791,0.073945,0.006019979,0.001166568,0.000101731,0.00431508,0.00000610564,0.54942,0.1212809,0.009873625,0.2301878],"study_design_scores_gemma":[0.01325623,0.003286422,0.06690253,0.00462088,0.003777422,0.0015611,0.005831471,0.0698325,0.1364579,0.08460723,0.6073009,0.002565447],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8214666,0.1632274,0.003916763,0.003001721,0.0004862472,0.0008052312,0.00008177754,0.0003389414,0.006675276],"genre_scores_gemma":[0.9943171,0.002494719,0.001345148,0.0001783936,0.0001202174,0.000154218,0.000217248,0.00002356793,0.001149359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5974272,"threshold_uncertainty_score":0.5741503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03511243310077641,"score_gpt":0.3166222558862614,"score_spread":0.281509822785485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}