{"id":"W4401504630","doi":"10.1021/jacs.4c06308","title":"Terpenoid Cyclophanes with Planar Chirality","year":2024,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; American Chemical Society Petroleum Research Fund","keywords":"Chemistry; Planar chirality; Chirality (physics); Planar; Terpenoid; Cyclophane; Stereochemistry; Computational chemistry; Crystallography; Organic chemistry; Enantioselective synthesis; Crystal structure; Catalysis; Chiral symmetry; Quantum mechanics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000710837,0.0001864356,0.0001145004,0.00009676912,0.0001001417,0.0001924195,0.0001163051,0.0001374374,0.002083875],"category_scores_gemma":[0.0001326456,0.00008159928,0.0001221188,0.00009068186,0.0001789554,0.0002448077,0.0002376432,0.0003372903,0.0004309572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000157448,"about_ca_system_score_gemma":0.0001828139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001787653,"about_ca_topic_score_gemma":0.0004538965,"domain_scores_codex":[0.9999455,0.000007940052,0.00000397658,0.00001418454,0.00001150908,0.00001687871],"domain_scores_gemma":[0.9999332,0.00001076127,0.00002027953,0.00001429253,0.000008580964,0.00001289625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009463955,0.0000207185,0.0002367751,0.0001174376,0.000007738032,0.0002988297,0.00004517315,0.0002948144,0.9889637,0.002573888,0.0001382525,0.007207915],"study_design_scores_gemma":[0.0000243036,0.0004018155,0.001470062,0.00001577832,0.00001379626,0.0006965101,0.00003967516,0.000719318,0.9834338,0.0004576445,0.01271942,0.000007896518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745228,0.001843641,0.006816497,0.0002351476,0.00005941415,0.00005343973,0.0003837433,0.0001067403,0.01597871],"genre_scores_gemma":[0.9910452,0.001458447,0.003639308,0.00006553494,0.00001184406,0.00002724872,0.0002260178,0.00002166627,0.003504636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002083875,"threshold_uncertainty_score":0.00697124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005166437272025703,"score_gpt":0.2238240411215538,"score_spread":0.2186576038495281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}