{"id":"W4401510369","doi":"10.1101/cshperspect.a041593","title":"The Role of B Lymphocytes in Type 1 Diabetes","year":2024,"lang":"en","type":"article","venue":"Cold Spring Harbor Perspectives in Medicine","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Pathogenesis; Immunology; Autoantibody; Bone marrow; Disease; Peripheral tolerance; Biology; Autoimmunity; Type 1 diabetes; Central tolerance; Self Tolerance; Antigen; Medicine; Immune tolerance; Diabetes mellitus; Antibody; Pathology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008073009,0.0004393704,0.0003233477,0.0006584884,0.000497482,0.0009355449,0.0003115171,0.001720329,0.002664377],"category_scores_gemma":[0.0004016799,0.0001651527,0.0002277773,0.0002024625,0.0009497223,0.0007244415,0.0006535025,0.002130931,0.0008367826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005162686,"about_ca_system_score_gemma":0.0005176473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007589853,"about_ca_topic_score_gemma":0.0009897565,"domain_scores_codex":[0.9997465,0.00008708224,0.00001599772,0.00003705901,0.00007303002,0.00004030567],"domain_scores_gemma":[0.999818,0.00007040812,0.00002116238,0.000008473661,0.00002592859,0.00005590303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009285751,0.0003161672,0.009994716,0.001968646,0.0001223407,0.00657921,0.0008481957,0.0007971968,0.09882689,0.07862166,0.08759848,0.7133978],"study_design_scores_gemma":[0.0001179453,0.000558342,0.01758537,0.0009882619,0.00009200776,0.006496038,0.0004182259,0.0004085252,0.007582589,0.0363478,0.9293524,0.00005249353],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02149375,0.8909769,0.001956359,0.04614976,0.006919229,0.00002310887,0.00006927686,0.00008251425,0.03232902],"genre_scores_gemma":[0.1545471,0.7653687,0.00414878,0.02574073,0.01647849,0.00006515856,0.00008268326,0.00003711401,0.03353121],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002664377,"threshold_uncertainty_score":0.008913279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004938096629839694,"score_gpt":0.240924320974986,"score_spread":0.2359862243451464,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}