{"id":"W4401511075","doi":"10.1136/gutjnl-2024-iddf.188","title":"IDDF2024-ABS-0201 Long-term safety profile of tenofovir alafenamide in chronic hepatitis B patients; final 8-year results of 2 phase 3 studies","year":2024,"lang":"en","type":"article","venue":"","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto Liver Centre; University Health Network","funders":"","keywords":"Tenofovir alafenamide; Medicine; Discontinuation; Adverse effect; Internal medicine; Gastroenterology; Incidence (geometry); HBeAg; Urology; Hepatitis B virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003810863,0.0007869798,0.001541997,0.0003184231,0.0003042299,0.0007293834,0.0005263988,0.001098009,0.001965556],"category_scores_gemma":[0.001070127,0.0002917495,0.001305963,0.0002953722,0.000367516,0.0004423523,0.0002161095,0.001638352,0.0006297442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004481838,"about_ca_system_score_gemma":0.001069262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009875289,"about_ca_topic_score_gemma":0.002129639,"domain_scores_codex":[0.9992877,0.0003884822,0.0000609501,0.00005215616,0.0001134786,0.00009716299],"domain_scores_gemma":[0.9990748,0.0001955731,0.0002673456,0.00006558555,0.0001345026,0.0002621329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5746104,0.02831868,0.02709701,0.001377581,0.004988016,0.0004812617,0.0002973408,0.002331236,0.07608871,0.0003494521,0.01077443,0.2732859],"study_design_scores_gemma":[0.4601448,0.4324436,0.07959004,0.0001566585,0.002351138,0.0007620044,0.0001017359,0.00189857,0.01132819,0.0003002427,0.01084661,0.00007637814],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810493,0.007906631,0.001299966,0.000692642,0.0001718166,0.002142235,0.003270027,0.0001666413,0.003300761],"genre_scores_gemma":[0.9857557,0.002806737,0.002175452,0.001341612,0.0002510138,0.001573888,0.003742909,0.00003330606,0.002319335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003810863,"threshold_uncertainty_score":0.02015406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03903358419471934,"score_gpt":0.3474160810875571,"score_spread":0.3083824968928377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}