{"id":"W4401519604","doi":"10.1111/tan.15628","title":"Calcium‐dependent <scp>HLA</scp>‐<scp>DQ</scp> epitope revealed by <scp>EDTA</scp> mediated inhibition of antibody reactions in the Luminex single antigen bead assay","year":2024,"lang":"en","type":"article","venue":"HLA","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Associação Fundo de Incentivo à Pesquisa","keywords":"Chemistry; Epitope; Ethylenediaminetetraacetic acid; Antibody; Antigen; Dithiothreitol; Molecular biology; Calcium; Chelation; Immunology; Biochemistry; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002750535,0.0002781585,0.0001883995,0.0001563691,0.0001241915,0.0002843623,0.000191115,0.0002869999,0.001238846],"category_scores_gemma":[0.0002409202,0.0001233254,0.000207164,0.00009233427,0.0001619355,0.00009689349,0.0001703493,0.0003468951,0.0004234879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001051076,"about_ca_system_score_gemma":0.00009654937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002775029,"about_ca_topic_score_gemma":0.0003497079,"domain_scores_codex":[0.9997264,0.00007059839,0.0000262402,0.00004377463,0.00008982082,0.00004314305],"domain_scores_gemma":[0.9998379,0.00004187011,0.00004994954,0.00002527267,0.00002760944,0.00001732183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006534519,0.00002216849,0.0007843513,0.00001564881,0.000004174359,0.00006284007,0.00001235482,0.00001543071,0.9983053,0.0000206015,0.00001897174,0.0006728545],"study_design_scores_gemma":[0.00001018815,0.0002959164,0.01694549,0.000004547255,0.00001926506,0.0009821367,0.00001529983,0.000625487,0.9798678,0.00002502794,0.001205744,0.000003066778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945716,0.0004326465,0.003625694,0.00005030437,0.00001198542,0.0000258041,0.00006986316,0.00003378161,0.001178286],"genre_scores_gemma":[0.994673,0.0002896548,0.003151003,0.00005010705,0.00001078402,0.00001948429,0.0001823797,0.00001021283,0.001613453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001238846,"threshold_uncertainty_score":0.004144371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02343457622313976,"score_gpt":0.2842623990537362,"score_spread":0.2608278228305965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}