{"id":"W4401519604","doi":"10.1111/tan.15628","title":"Calcium‐dependent <scp>HLA</scp>‐<scp>DQ</scp> epitope revealed by <scp>EDTA</scp> mediated inhibition of antibody reactions in the Luminex single antigen bead assay","year":2024,"lang":"en","type":"article","venue":"HLA","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Associação Fundo de Incentivo à Pesquisa","keywords":"Chemistry; Epitope; Ethylenediaminetetraacetic acid; Antibody; Antigen; Dithiothreitol; Molecular biology; Calcium; Chelation; Immunology; Biochemistry; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001701998,0.0005397599,0.0007633608,0.0005577902,0.0003169568,0.0001188988,0.0006364746,0.0005183347,0.0001568529],"category_scores_gemma":[0.00282178,0.0004594892,0.0003268766,0.000978223,0.0003481383,0.0003304992,0.0002650743,0.0007519185,0.001076166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000189694,"about_ca_system_score_gemma":0.0001995942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007726058,"about_ca_topic_score_gemma":0.0002421278,"domain_scores_codex":[0.9950753,0.001455174,0.001296424,0.0008882879,0.0003236738,0.0009611669],"domain_scores_gemma":[0.9932233,0.00510808,0.000472185,0.0008890178,0.000210677,0.0000967562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004993862,0.000705473,0.01533205,0.0002370725,0.0002593312,0.00008169215,0.00177921,0.000008299892,0.7588699,0.0003415056,0.2221836,0.0001969283],"study_design_scores_gemma":[0.002875971,0.0005737589,0.0647234,0.001326907,0.0004545329,0.000328603,0.01090026,0.00008381416,0.373529,0.0004818447,0.5445222,0.0001997504],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9725164,0.01461873,0.0003330481,0.0002530617,0.00177922,0.0013594,0.001508326,0.0003256326,0.007306208],"genre_scores_gemma":[0.9871728,0.0004806529,0.00002734671,0.0002045635,0.0001974989,0.0001723517,0.003999332,0.00007897262,0.007666458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3853409,"threshold_uncertainty_score":0.9997857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02343457622313976,"score_gpt":0.2842623990537362,"score_spread":0.2608278228305965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}