{"id":"W4401532996","doi":"10.1002/anie.202411156","title":"Stereodivergency in Copper‐Catalyzed Borylative Difunctionalizations: The Impact of Boron Coordination","year":2024,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Organoboron and organosilicon chemistry","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Reagent; Aldol reaction; Diastereomer; Steric effects; Catalysis; Copper; Combinatorial chemistry; Borylation; Boron; Lewis acids and bases; Adduct; Selectivity; Coordination complex; Computational chemistry; Organic chemistry; Aryl","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003293197,0.000461748,0.00026516,0.0001535343,0.000251647,0.0003319147,0.0003725805,0.0002035952,0.002366676],"category_scores_gemma":[0.000289301,0.0001949451,0.0001245082,0.00015218,0.0004023554,0.0003593197,0.00034939,0.0004238371,0.0002920503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004486606,"about_ca_system_score_gemma":0.000327334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008408181,"about_ca_topic_score_gemma":0.001441218,"domain_scores_codex":[0.9998485,0.00002587849,0.000007691362,0.00002822865,0.00002839768,0.00006126715],"domain_scores_gemma":[0.9999305,0.00002211103,0.00001811078,0.00001049513,0.000007978798,0.00001080204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008581853,0.0001540352,0.0005540903,0.000574902,0.00003552299,0.0003949948,0.0002681085,0.007450012,0.9451143,0.02305051,0.0008278163,0.02071752],"study_design_scores_gemma":[0.0001029616,0.0008430785,0.0007878065,0.00002393154,0.00002620174,0.0001718674,0.00007801996,0.01338668,0.9769532,0.001792034,0.005792562,0.00004166357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789996,0.0008447994,0.007604823,0.0001343458,0.00004648533,0.00003809598,0.0001243472,0.0001732081,0.0120344],"genre_scores_gemma":[0.9977108,0.0003924907,0.001288828,0.00002344915,0.000003372512,0.00001182683,0.00003254723,0.00001901527,0.0005177516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002366676,"threshold_uncertainty_score":0.007917285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01435977080412367,"score_gpt":0.2846315612539743,"score_spread":0.2702717904498506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}