{"id":"W4401534720","doi":"10.1093/ehjopen/oeae062","title":"Colchicine for cardiovascular and limb risk reduction in Medicare beneficiaries with peripheral artery disease: emulation of target trials","year":2024,"lang":"en","type":"article","venue":"European Heart Journal Open","topic":"Peripheral Artery Disease Management","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Brigham and Women's Hospital","keywords":"Medicine; Mace; Internal medicine; Colchicine; Gout; Adverse effect; Confounding; Randomized controlled trial; Surgery; Physical therapy; Percutaneous coronary intervention; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003295658,0.0001537062,0.0006201225,0.0001686028,0.0001157006,0.000211055,0.0000951437,0.00001924306,0.0001051548],"category_scores_gemma":[0.0002837694,0.0001075805,0.0002765416,0.0001724203,0.00005302487,0.0003308149,0.00007461077,0.0002102498,0.000003292216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007786713,"about_ca_system_score_gemma":0.0001278211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000209782,"about_ca_topic_score_gemma":0.000007526517,"domain_scores_codex":[0.9979402,0.0006634457,0.0005883127,0.0002790383,0.000351035,0.0001779852],"domain_scores_gemma":[0.9992385,0.00007908901,0.0001190165,0.000223832,0.0001082349,0.0002313397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.07498191,0.002652809,0.3580204,0.008361043,0.02340162,0.009408364,0.01714625,0.09154289,0.008584342,0.001744794,0.09009297,0.3140626],"study_design_scores_gemma":[0.00867016,0.002438378,0.7660421,0.003562458,0.002602253,0.000748639,0.001220491,0.009167183,0.00007358353,0.000652025,0.2044297,0.0003930902],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9702327,0.01641937,0.003020109,0.006801724,0.0004072264,0.00242288,0.00008234788,0.00004099222,0.0005727169],"genre_scores_gemma":[0.9958647,0.0004777429,0.002614222,0.0001538142,0.0005629093,0.00002461624,0.00004408553,0.00004448012,0.0002133575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4080217,"threshold_uncertainty_score":0.4387004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05575457965162646,"score_gpt":0.3335736294998402,"score_spread":0.2778190498482137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}