{"id":"W4401536701","doi":"10.1523/jneurosci.1574-23.2024","title":"The Lysine Acetyltransferase PCAF Functionally Interacts with Estrogen Receptor Alpha in the Hippocampus of Gonadally Intact Male—But Not Female—Rats to Enhance Short-Term Memory","year":2024,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; York University","funders":"Natural Sciences and Engineering Research Council of Canada; Università degli Studi di Salerno; Regione Campania; Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"PCAF; Hippocampus; Endocrinology; Acetyltransferase; Estrogen receptor alpha; Internal medicine; Estrogen; Estrogen receptor; Chemistry; Biology; Medicine; Biochemistry; Acetylation; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001354244,0.0005193704,0.0004231034,0.0005390117,0.0001754196,0.0002325119,0.0002600954,0.0002320934,0.001667519],"category_scores_gemma":[0.0001891476,0.0003400302,0.000412168,0.0001937604,0.0004461452,0.0002777657,0.0001988829,0.001041017,0.0004858933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003724575,"about_ca_system_score_gemma":0.0003619035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001639623,"about_ca_topic_score_gemma":0.003072995,"domain_scores_codex":[0.9997643,0.00001989751,0.00001332505,0.00006621991,0.0000541517,0.00008213911],"domain_scores_gemma":[0.9997454,0.00002283827,0.0000707064,0.00003211728,0.00002089294,0.0001081039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001091559,0.0001069899,0.0003816658,0.0000200943,0.00001306999,0.00005623147,0.0000253583,0.00002561326,0.9965753,0.00005595251,0.0000445872,0.001603635],"study_design_scores_gemma":[0.0001361495,0.002973267,0.01984055,0.000007632436,0.00007628561,0.0002841063,0.0001237048,0.0005800175,0.9742993,0.00009575416,0.001566545,0.00001659885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996897,0.00081043,0.001065317,0.0001646843,0.00007041873,0.00001382987,0.0003214995,0.00005418773,0.0006025499],"genre_scores_gemma":[0.9917552,0.0009826646,0.001155272,0.0001036509,0.00004471201,0.00006699003,0.0005386653,0.00004434439,0.00530849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001667519,"threshold_uncertainty_score":0.005578458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01477755028378849,"score_gpt":0.2896733148201501,"score_spread":0.2748957645363616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}