{"id":"W4401562606","doi":"10.1016/j.niox.2024.08.001","title":"Cystathionine gamma-lyase deficiency exaggerates diethylnitrosamine-induced liver damage in mice","year":2024,"lang":"en","type":"article","venue":"Nitric Oxide","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Laurentian University","funders":"Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Cystathionine beta synthase; Cystathionine gamma-lyase; Lyase; Chemistry; Transsulfuration; Enzyme; Biochemistry; Cysteine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003587908,0.001089238,0.0005575048,0.001526105,0.000372041,0.0004943016,0.0004020657,0.0007357015,0.001739685],"category_scores_gemma":[0.0002644561,0.0007713502,0.0005137787,0.0003742139,0.0007688152,0.00052127,0.0003672361,0.001239451,0.0005372259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004996453,"about_ca_system_score_gemma":0.0003990215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009465032,"about_ca_topic_score_gemma":0.002076874,"domain_scores_codex":[0.9996543,0.00006379216,0.00003939419,0.00008362728,0.00007675264,0.00008205351],"domain_scores_gemma":[0.9992675,0.00005969152,0.0002776929,0.00008311408,0.00004281439,0.0002692413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001207306,0.0001805776,0.0006239741,0.00003644227,0.00001882495,0.0001432593,0.00002785011,0.00009869777,0.9965809,0.0001457393,0.0000470048,0.0008895778],"study_design_scores_gemma":[0.0001418169,0.001498027,0.01061131,0.00001960398,0.0001079428,0.0006452486,0.0001033385,0.0009986765,0.9844204,0.0002043214,0.001232118,0.00001728244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964783,0.0006343107,0.001130253,0.0002068937,0.00004545558,0.00002767436,0.0003561883,0.0002109134,0.000910075],"genre_scores_gemma":[0.9922503,0.0008656924,0.001264359,0.0001078327,0.00003441266,0.00004985351,0.0004136454,0.00009095912,0.004922938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001739685,"threshold_uncertainty_score":0.005819798,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01579545267234556,"score_gpt":0.2640181926459476,"score_spread":0.248222739973602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}