{"id":"W4401595886","doi":"10.1093/ibd/izae163","title":"Comparative Efficacy of Biologics and Small Molecule Therapies in Improving Patient-Reported Outcomes in Ulcerative Colitis: Systematic Review and Network Meta-Analysis","year":2024,"lang":"en","type":"review","venue":"Inflammatory Bowel Diseases","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; McMaster University; Population Health Research Institute; University of Calgary; McGill University Health Centre","funders":"","keywords":"Medicine; Internal medicine; Meta-analysis; Ulcerative colitis; Odds ratio; Confidence interval; Quality of life (healthcare); Clinical endpoint; Placebo; MEDLINE; Inflammatory bowel disease; Randomized controlled trial; Physical therapy; Disease; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01555736,0.002477902,0.02152799,0.007387805,0.0005605248,0.002872615,0.002256579,0.002162228,0.003307785],"category_scores_gemma":[0.03849832,0.001121992,0.0327857,0.007695068,0.0008174863,0.001779496,0.001490484,0.001906853,0.0002231609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002601834,"about_ca_system_score_gemma":0.003086117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005187171,"about_ca_topic_score_gemma":0.01074429,"domain_scores_codex":[0.9865612,0.007499501,0.003127198,0.001209254,0.001303329,0.0002995323],"domain_scores_gemma":[0.969958,0.02324088,0.004486498,0.000635948,0.00138537,0.0002933343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002303586,0.00002692196,0.002843515,0.3508295,0.6347793,0.00007225897,0.00004513234,0.0005504102,0.0001372692,0.0001003831,0.0003566961,0.007954956],"study_design_scores_gemma":[0.00077489,0.0002089004,0.002643777,0.0192557,0.9757186,0.00006133671,0.00002652736,0.000207306,0.0000796795,0.0001486538,0.0008568269,0.00001783346],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005023866,0.9932142,0.0004241799,0.0001581069,0.0001075669,0.0002801453,0.0005665494,0.00002085685,0.0002044747],"genre_scores_gemma":[0.2311128,0.7622164,0.002524087,0.0008716525,0.0003091815,0.001460206,0.001200719,0.00003416679,0.0002708042],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02152799,"threshold_uncertainty_score":0.08227617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04341262383495992,"score_gpt":0.314691550622578,"score_spread":0.2712789267876181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}