{"id":"W4401622494","doi":"10.3389/fimmu.2024.1421346","title":"Aryl hydrocarbon receptor: current perspectives on key signaling partners and immunoregulatory role in inflammatory diseases","year":2024,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Kuwait Foundation for the Advancement of Sciences","keywords":"Aryl hydrocarbon receptor; Aryl hydrocarbon receptor nuclear translocator; Transcription factor; Immune system; Biology; Cell biology; Innate immune system; Signal transduction; Acquired immune system; Receptor; Immunology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003517213,0.0007284863,0.0007959241,0.001301813,0.0002449756,0.0008942331,0.0005883499,0.000879171,0.007436636],"category_scores_gemma":[0.0004102951,0.0001644877,0.0003346,0.001735436,0.0003902296,0.001277995,0.0006797888,0.001784296,0.004394618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004519872,"about_ca_system_score_gemma":0.0009109613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00061496,"about_ca_topic_score_gemma":0.001196405,"domain_scores_codex":[0.9998773,0.00002056876,0.0000139905,0.0000231842,0.00004761854,0.00001731475],"domain_scores_gemma":[0.9998347,0.00005424773,0.00002061412,0.000005777276,0.0000541093,0.00003059979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009999094,0.00006036004,0.0001616197,0.01017203,0.00005538532,0.0001586357,0.00006092374,0.0002101633,0.003320795,0.00532244,0.06193009,0.9184476],"study_design_scores_gemma":[0.000008132178,0.00004689851,0.0004185663,0.001011234,0.00003255304,0.0005029775,0.00003212072,0.00003264457,0.0002296439,0.001607106,0.99607,0.000007973777],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008690382,0.9971122,0.0001457271,0.0004365277,0.0005960572,0.00000335818,0.0000226587,0.00001086735,0.001585761],"genre_scores_gemma":[0.0005981048,0.9967042,0.0001519933,0.0003396942,0.0005591778,0.000005028745,0.00004455679,0.000002030613,0.001595351],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007436636,"threshold_uncertainty_score":0.02487803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01177674715559597,"score_gpt":0.2709991569175187,"score_spread":0.2592224097619228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}