{"id":"W4401699691","doi":"10.61186/nl.3.3.13","title":"White matter integrity changes in mild cognitive impairment associated with Aspirin use","year":2024,"lang":"en","type":"article","venue":"Neurology Letters","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; Pfizer; Novartis Pharmaceuticals Corporation; University of Southern California; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; BioClinica; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; Alzheimer's Association","keywords":"Cognitive impairment; Aspirin; White matter; Cognition; Medicine; Psychology; Internal medicine; Psychiatry; Magnetic resonance imaging; Radiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001021509,0.0001798117,0.0002311694,0.0002546894,0.00003042018,0.00003346081,0.00004775311,0.00009427331,0.0002510903],"category_scores_gemma":[0.00002563583,0.0001309174,0.00005444906,0.0002426767,0.0001614941,0.00009078032,0.00004030203,0.0006449801,0.0002538461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006624434,"about_ca_system_score_gemma":0.00006446202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001191773,"about_ca_topic_score_gemma":0.0003903779,"domain_scores_codex":[0.998633,0.0001787242,0.0001158083,0.0003985405,0.00022729,0.0004466483],"domain_scores_gemma":[0.9994361,0.0002082802,0.00002367625,0.0001369927,0.00003579944,0.0001591372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001112611,0.0003203028,0.9833887,0.00003647931,0.001831456,0.007859747,0.0001342126,0.000001014165,0.00005180513,0.000002736178,0.005179718,0.00008126747],"study_design_scores_gemma":[0.002075528,0.001168139,0.9957426,0.0002244227,0.0003018995,0.00008067855,0.00001357329,0.00007950788,0.0001212077,0.000008824511,0.00008271124,0.0001009174],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.94222,0.000265903,0.000004226764,0.05659046,0.00007951252,0.0005301551,0.00005912342,0.00007934624,0.0001713204],"genre_scores_gemma":[0.9642595,0.00002021351,0.00001111031,0.03532599,0.00004790056,0.0001191678,0.0001327812,0.00003151483,0.00005179927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02203957,"threshold_uncertainty_score":0.5338656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03403540521652702,"score_gpt":0.301222784699154,"score_spread":0.267187379482627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}