{"id":"W4401731866","doi":"10.1016/j.cub.2024.07.089","title":"A conserved germline-specific Dsn1 alternative splice isoform supports oocyte and embryo development","year":2024,"lang":"en","type":"article","venue":"Current Biology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Biology; Cohesin; Germline; Meiosis; Oocyte; Genetics; Somatic cell; Chromosome segregation; Mitosis; Cell biology; Kinetochore; Chromosome; Embryo; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001422968,0.0002301391,0.0001521443,0.0001614954,0.000234214,0.0002882374,0.0002976305,0.00032806,0.002631369],"category_scores_gemma":[0.0001454571,0.00009427049,0.000186008,0.00007113537,0.0002588358,0.0002002516,0.0002131794,0.0004856137,0.0006243376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004469538,"about_ca_system_score_gemma":0.0002852244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007537776,"about_ca_topic_score_gemma":0.002448585,"domain_scores_codex":[0.9999063,0.000008358413,0.000008447154,0.00003528513,0.00002458287,0.00001705159],"domain_scores_gemma":[0.9998388,0.00001583641,0.00004900754,0.00001832744,0.00002289993,0.00005508632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006085791,0.000005939654,0.0002526072,0.0000114888,0.000003290236,0.0001068061,0.000004174838,0.00003598511,0.9984159,0.000380358,0.00004077749,0.0006817789],"study_design_scores_gemma":[0.0000309072,0.0000875336,0.01209164,0.000009466937,0.00002550842,0.001441771,0.00005204343,0.001528498,0.9775807,0.0003300171,0.006813621,0.00000836916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905636,0.0007505023,0.003888667,0.0002058847,0.0001057486,0.0000131629,0.0004351456,0.00007844429,0.003958753],"genre_scores_gemma":[0.9951035,0.0002603529,0.001864738,0.00007663865,0.00001476829,0.000006903882,0.0004373236,0.00004441295,0.002191444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002631369,"threshold_uncertainty_score":0.008802772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02052376747095371,"score_gpt":0.2892826819113348,"score_spread":0.2687589144403811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}