{"id":"W4401763915","doi":"10.3354/dao03817","title":"PirA- or PirB-binding nanobodies can protect whiteleg shrimp from the acute hepatopancreatic necrosis disease toxin","year":2024,"lang":"en","type":"article","venue":"Diseases of Aquatic Organisms","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Toxin; Necrosis; Penaeidae; Shrimp; Decapoda; Virology; Microbiology; Fishery; Genetics; Crustacean","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002682206,0.0005097769,0.0006768515,0.0001780364,0.000443092,0.0001663775,0.0007764906,0.0001891982,0.003005644],"category_scores_gemma":[0.0007051801,0.0003253668,0.0003351326,0.0005329587,0.0004536313,0.0002009151,0.0002883886,0.0003397938,0.001262917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001400953,"about_ca_system_score_gemma":0.0008689265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000819065,"about_ca_topic_score_gemma":0.0001215045,"domain_scores_codex":[0.9972224,0.0006001104,0.0006635633,0.0006602451,0.0001936831,0.0006599528],"domain_scores_gemma":[0.9975699,0.001107095,0.000195565,0.0009447695,0.00006282505,0.0001198976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001846077,0.0003733967,0.005608357,0.0003251163,0.002470379,0.0003176166,0.004112085,0.000003781189,0.9727954,0.001930423,0.00540586,0.004811499],"study_design_scores_gemma":[0.002135164,0.0008080085,0.009453946,0.001475546,0.004258086,0.00006497691,0.001948387,0.0004086599,0.9662124,0.01036223,0.001792068,0.001080517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790182,0.01341735,0.0005480573,0.002046543,0.001237123,0.001319953,0.0019926,0.0003802931,0.00003993327],"genre_scores_gemma":[0.9950271,0.0002614842,0.0001810302,0.0004981171,0.00006966288,0.000215019,0.0004910827,0.000112637,0.003143908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01600891,"threshold_uncertainty_score":0.9999198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01223601440762674,"score_gpt":0.2355071861888712,"score_spread":0.2232711717812445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}