{"id":"W4401793484","doi":"10.1016/j.yhbeh.2024.105616","title":"Pregnancy history and estradiol influence spatial memory, hippocampal plasticity, and inflammation in middle-aged rats","year":2024,"lang":"en","type":"article","venue":"Hormones and Behavior","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health; University of British Columbia","funders":"","keywords":"Pregnancy; Neuroplasticity; Hippocampus; Morris water navigation task; Hippocampal formation; Internal medicine; Endocrinology; Medicine; Estrogen; Physiology; Psychology; Neuroscience; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001869114,0.0005526556,0.0004238462,0.0007620121,0.0002383162,0.0003344766,0.000250217,0.0003123132,0.001128371],"category_scores_gemma":[0.0002142214,0.0003826353,0.000427521,0.0002180755,0.0004967364,0.0004094111,0.0003478017,0.001000175,0.0002132333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004765981,"about_ca_system_score_gemma":0.000408493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002051942,"about_ca_topic_score_gemma":0.004035474,"domain_scores_codex":[0.9997931,0.00002042551,0.00002006474,0.0000577156,0.00003611681,0.00007266202],"domain_scores_gemma":[0.9996147,0.00002895139,0.0001413965,0.00003862158,0.00003095592,0.0001452903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01006959,0.001321484,0.006833452,0.00008157849,0.00005417456,0.0004095382,0.0002916545,0.00007253313,0.9722034,0.0002029022,0.0001511631,0.008308494],"study_design_scores_gemma":[0.0003783086,0.02111996,0.1593014,0.00005064756,0.000335815,0.0008671083,0.0007611145,0.0007961261,0.8107874,0.0006995408,0.004816816,0.00008589663],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973829,0.001381602,0.0004134287,0.00007894598,0.00003730848,0.00001177491,0.0002202934,0.00003334145,0.0004402926],"genre_scores_gemma":[0.9925988,0.002045533,0.0009345161,0.0001433291,0.00002112474,0.00008040447,0.0003381467,0.00001647121,0.003821719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002051942,"threshold_uncertainty_score":0.004079998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02049101851456546,"score_gpt":0.2285066564159487,"score_spread":0.2080156379013832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}