{"id":"W4401794081","doi":"10.2196/54740","title":"Predictive Models for Long Term Survival of AML Patients Treated with Venetoclax and Azacitidine or 7+3 Based on Post Treatment Events and Responses: Retrospective Cohort Study","year":2024,"lang":"en","type":"article","venue":"JMIR Cancer","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Azacitidine; Venetoclax; Oncology; Medicine; Retrospective cohort study; Term (time); Internal medicine; Cohort; Overall survival; Leukemia; Biology; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001677832,0.000243498,0.0004902039,0.0002224344,0.00006463893,0.0000187636,0.00004637464,0.00007465114,0.00003363162],"category_scores_gemma":[0.0000425144,0.0001489398,0.00004585405,0.0002597318,0.0001044599,0.00009774659,0.00002749915,0.0001329445,5.202469e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00242606,"about_ca_system_score_gemma":0.0007859125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005386007,"about_ca_topic_score_gemma":0.0003627102,"domain_scores_codex":[0.9984146,0.00009087138,0.0002097947,0.0005604555,0.000467475,0.0002568429],"domain_scores_gemma":[0.9989919,0.0002272709,0.0000599724,0.0002499792,0.0003252124,0.0001456507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.04323608,0.0005497953,0.9520702,0.0001968908,0.0008054419,0.0000896835,0.000889797,0.0000752204,0.0001575556,0.000003178215,0.00004700574,0.001879184],"study_design_scores_gemma":[0.0105224,0.02562121,0.9481719,0.0005591256,0.0004034404,0.000004279842,0.000152479,0.01386875,0.0005423866,0.000004782303,0.00001684942,0.0001323911],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914545,0.0001180734,0.00007736054,0.0001037564,0.00004253053,0.006847127,0.001206935,0.00004663104,0.0001030372],"genre_scores_gemma":[0.995818,0.0001014971,0.00003320043,0.00003198326,0.00006482353,0.002566305,0.0001190001,0.00005685617,0.001208372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03271369,"threshold_uncertainty_score":0.6344063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0255818591277965,"score_gpt":0.3438037883121537,"score_spread":0.3182219291843573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}