{"id":"W4401794190","doi":"10.1038/s41586-024-07853-8","title":"Oligodendrocytes and myelin limit neuronal plasticity in visual cortex","year":2024,"lang":"en","type":"article","venue":"Nature","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Eye Institute; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institutes of Health; Dr. Miriam and Sheldon G. Adelson Medical Research Foundation; University of California, San Francisco; National Alliance for Research on Schizophrenia and Depression; Canadian Institutes of Health Research","keywords":"Neuroscience; Myelin; Visual cortex; Plasticity; Neuroplasticity; Biology; Cortex (anatomy); Central nervous system; Physics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001341402,0.000222268,0.0002152131,0.0002600361,0.0001638981,0.0003599286,0.0004447713,0.000339159,0.0005605515],"category_scores_gemma":[0.0002935972,0.000141347,0.0000859127,0.00007285184,0.0005362028,0.0002899767,0.0004482028,0.000436971,0.0001390126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005546591,"about_ca_system_score_gemma":0.000401579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001245719,"about_ca_topic_score_gemma":0.002312418,"domain_scores_codex":[0.999889,0.00001118682,0.000005570356,0.00001855253,0.00004537822,0.00003020778],"domain_scores_gemma":[0.9995841,0.00005315812,0.0001933078,0.0000223265,0.00004549371,0.0001016392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001022026,0.00001427942,0.000578596,0.00004958034,0.000004437358,0.000069671,0.00002442587,0.00013358,0.9962112,0.0006931099,0.00003870357,0.002080267],"study_design_scores_gemma":[0.00005240925,0.0006916322,0.06086869,0.00004243449,0.00003750513,0.0008013294,0.0001319632,0.002991758,0.9271677,0.003085322,0.004111628,0.0000177849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924326,0.00359193,0.00229876,0.00007749515,0.00001416957,0.0000088738,0.00006094952,0.00005513555,0.001459991],"genre_scores_gemma":[0.9963878,0.001077653,0.001085563,0.00003728021,0.000008022245,0.00001223891,0.00004443712,0.00001358385,0.001333428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001245719,"threshold_uncertainty_score":0.004024386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01527689421759711,"score_gpt":0.2778206414403454,"score_spread":0.2625437472227483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}