{"id":"W4401836062","doi":"10.1101/2024.08.20.608742","title":"A Human Biomimetic Intestinal Mucosa Model to Study Gastrointestinal Development and Disease","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; Stemcell Technologies","funders":"","keywords":"Immune system; Cell biology; Biology; Intestinal mucosa; Extracellular matrix; Crosstalk; Immunology; Inflammation; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005843424,0.0004839256,0.0002968809,0.0005078984,0.0001842385,0.0004236424,0.0002866381,0.0006473057,0.002568517],"category_scores_gemma":[0.0001578793,0.0002069196,0.0003673832,0.0003060744,0.0003294742,0.0003299312,0.0004711237,0.0009260856,0.0007870893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002762904,"about_ca_system_score_gemma":0.0002839686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004959896,"about_ca_topic_score_gemma":0.0006432606,"domain_scores_codex":[0.999814,0.00004380962,0.00001332319,0.00005076706,0.00005322057,0.0000248675],"domain_scores_gemma":[0.9998444,0.00003456635,0.00003333515,0.0000383166,0.00001682314,0.00003251738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00013943,0.00006708073,0.0002141482,0.00009573646,0.00000805588,0.0001507438,0.00002503217,0.0002147017,0.9962902,0.0003675295,0.0002172328,0.002210045],"study_design_scores_gemma":[0.00006472366,0.001578934,0.005409409,0.00006241211,0.00008301153,0.002171188,0.0001271833,0.005042403,0.9510253,0.0004973675,0.03391564,0.00002245887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8351378,0.01468851,0.1318631,0.0009165542,0.0008726084,0.0006241639,0.003316516,0.001022816,0.01155796],"genre_scores_gemma":[0.9257121,0.00462229,0.05746105,0.0003316044,0.00007102209,0.0006387887,0.002009147,0.000140033,0.009013922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002568517,"threshold_uncertainty_score":0.008592546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02132322777295186,"score_gpt":0.2495786877839304,"score_spread":0.2282554600109786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}