{"id":"W4401876389","doi":"10.1016/s2152-2650(24)01687-2","title":"MM-488 Iberdomide, Bortezomib, and Dexamethasone (IberVd) in Transplant-Ineligible Newly Diagnosed Multiple Myeloma (NDMM): Results From the CC-220-MM-001 Trial","year":2024,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; Dalhousie University","funders":"","keywords":"Medicine; Bortezomib; Multiple myeloma; Dexamethasone; Internal medicine; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001210887,0.0009583338,0.001580345,0.0002326802,0.0002340184,0.00139149,0.0006653579,0.0008277261,0.003166133],"category_scores_gemma":[0.001142275,0.0003066442,0.001538265,0.0003895901,0.0006152944,0.0007120272,0.0004038038,0.002713071,0.000666946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009590422,"about_ca_system_score_gemma":0.0007896582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001555392,"about_ca_topic_score_gemma":0.004103377,"domain_scores_codex":[0.9994397,0.0003217197,0.00002037267,0.0000703003,0.00003794899,0.0001099714],"domain_scores_gemma":[0.9994557,0.000120864,0.0001396392,0.00004026936,0.00001934529,0.0002241611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8910158,0.004194613,0.008295897,0.0009105415,0.002580432,0.0001099343,0.00008368401,0.001457733,0.00534168,0.0006547978,0.007810532,0.0775444],"study_design_scores_gemma":[0.879091,0.07130037,0.03318297,0.0002163796,0.00327992,0.0002961652,0.0001373493,0.001116054,0.001405699,0.001232684,0.008684896,0.00005650389],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9763018,0.01355975,0.0002925682,0.001673976,0.0003807504,0.0003810737,0.00231183,0.0001075071,0.004990638],"genre_scores_gemma":[0.9874824,0.005269162,0.000342517,0.001319433,0.0002782962,0.0002780456,0.003036611,0.00002491615,0.001968674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003166133,"threshold_uncertainty_score":0.0105918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05143683475903155,"score_gpt":0.347134294064556,"score_spread":0.2956974593055245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}