{"id":"W4401877094","doi":"10.1016/s2152-2650(24)00789-4","title":"Deciphering the Clinical Benefit of Pola-R-CHP versus R-CHOP in Different Genetic Subtypes Beyond Cell of Origin (COO) in the POLARIX Study","year":2024,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Spinal Cord Injury BC; University of British Columbia; Roche (Canada)","funders":"","keywords":"Medicine; CHOP; Oncology; Internal medicine; Cancer research; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00388332,0.0005050669,0.001327188,0.0002867682,0.000345741,0.001750149,0.0004497862,0.0005637527,0.002945164],"category_scores_gemma":[0.002113829,0.0002008225,0.001130944,0.0004458587,0.0006477167,0.001033621,0.000743147,0.001518831,0.0005516076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000732242,"about_ca_system_score_gemma":0.0008475594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007966734,"about_ca_topic_score_gemma":0.001545354,"domain_scores_codex":[0.9988531,0.0005701671,0.00005582767,0.0002195223,0.00009652506,0.0002047848],"domain_scores_gemma":[0.9985389,0.000701648,0.0002041135,0.0001719774,0.00008319355,0.0003002009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.3119795,0.001471599,0.3985674,0.0005500846,0.005370209,0.0005559017,0.0005530882,0.002607047,0.03319296,0.003097774,0.004710859,0.2373435],"study_design_scores_gemma":[0.03001863,0.06388518,0.8050722,0.0005016598,0.01181287,0.002111607,0.002078466,0.005736168,0.01544773,0.01090805,0.05228522,0.0001423287],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988388,0.005210284,0.0008240207,0.001149249,0.0001204104,0.00007802307,0.0008262587,0.00001897531,0.003384728],"genre_scores_gemma":[0.9958705,0.0008804661,0.0005099264,0.0005820846,0.0002064294,0.00005704335,0.001177709,0.00002169599,0.0006940147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00388332,"threshold_uncertainty_score":0.0205372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03292318217930183,"score_gpt":0.3422123431779536,"score_spread":0.3092891609986518,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}