{"id":"W4401877238","doi":"10.1016/s2152-2650(24)01664-1","title":"MM-328 Efficacy and Safety of Teclistamab in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) With High-Risk (HR) Features: a Subgroup Analysis From the Phase 1/2 MajesTEC-1 Study","year":2024,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research; University of Calgary","funders":"","keywords":"Medicine; Subgroup analysis; Internal medicine; Oncology; Multiple myeloma; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001108107,0.0007577564,0.002051793,0.0004568499,0.0003117013,0.0008875803,0.0003640495,0.0005629312,0.001371429],"category_scores_gemma":[0.0009854358,0.00028188,0.002731218,0.0004582009,0.0003042633,0.0005153757,0.000418491,0.001025743,0.0002579373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006006222,"about_ca_system_score_gemma":0.000508869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006145768,"about_ca_topic_score_gemma":0.001796928,"domain_scores_codex":[0.9994525,0.0002339006,0.00005408073,0.00009368476,0.00006760157,0.00009822405],"domain_scores_gemma":[0.9995833,0.00009494708,0.000137169,0.00006282762,0.00003006014,0.0000917759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6268697,0.003187,0.2346103,0.001042727,0.02197596,0.0004220841,0.0002192297,0.002519011,0.01960916,0.0002563252,0.00289917,0.08638933],"study_design_scores_gemma":[0.2071756,0.0880254,0.6625318,0.0002216541,0.0248843,0.001153613,0.000418937,0.004190096,0.003779293,0.001199574,0.006278098,0.0001416238],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961303,0.002646808,0.00008185242,0.0001382359,0.0000348943,0.00008213291,0.0004753348,0.00001114034,0.0003992718],"genre_scores_gemma":[0.9977033,0.0005373437,0.0001048655,0.000169717,0.00006637102,0.00007111702,0.0010814,0.000005094182,0.0002608614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002051793,"threshold_uncertainty_score":0.005860329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01636859731662604,"score_gpt":0.3111379459528655,"score_spread":0.2947693486362394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}