{"id":"W4401898949","doi":"10.1055/s-0044-1789183","title":"Platelet-Type von Willebrand Disease: Complex Pathophysiology and Insights on Novel Therapeutic and Diagnostic Strategies","year":2024,"lang":"en","type":"review","venue":"Seminars in Thrombosis and Hemostasis","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Lawrence College; Carleton University; Queen's University","funders":"","keywords":"Von Willebrand disease; Von Willebrand factor; Platelet; Platelet disorder; Alloimmunity; Immunology; Medicine; Platelet membrane glycoprotein; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00214924,0.0008826237,0.001426308,0.001445706,0.0003056233,0.002224323,0.001169035,0.002391985,0.003756438],"category_scores_gemma":[0.001331068,0.0002525618,0.0007169378,0.0007329394,0.001156813,0.002489305,0.001253061,0.002945707,0.001264362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001160509,"about_ca_system_score_gemma":0.001319155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004518543,"about_ca_topic_score_gemma":0.0006734771,"domain_scores_codex":[0.9995933,0.0001477754,0.0000342571,0.0000652798,0.00008685468,0.00007257776],"domain_scores_gemma":[0.9993167,0.0002704183,0.00007555785,0.00004119406,0.000168411,0.0001277352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008540562,0.0006005515,0.001970956,0.006281542,0.0003039144,0.002448506,0.0002242864,0.002058342,0.008579736,0.07346084,0.0803486,0.8228688],"study_design_scores_gemma":[0.0003449526,0.001641256,0.004349726,0.008168654,0.0004719942,0.007562154,0.000571895,0.004973824,0.003705265,0.1185211,0.849526,0.0001632276],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002383413,0.9746937,0.002540192,0.01577938,0.001220996,0.00002574256,0.00007083834,0.00005954228,0.003226106],"genre_scores_gemma":[0.02609582,0.954233,0.004336047,0.006489139,0.006341216,0.00009722056,0.0001965444,0.00002378438,0.002187099],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003756438,"threshold_uncertainty_score":0.01256651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07752620861554585,"score_gpt":0.3667959891426307,"score_spread":0.2892697805270849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}