{"id":"W4401912326","doi":"10.1002/mbo3.1433","title":"Vitamin B<sub>12</sub> as a source of variability in isotope effects for chloroform biotransformation by <i>Dehalobacter</i>","year":2024,"lang":"en","type":"article","venue":"MicrobiologyOpen","topic":"Porphyrin Metabolism and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Helmholtz-Zentrum für Umweltforschung; European Regional Development Fund; University of Toronto; Natural Sciences and Engineering Research Council of Canada; Canadian Institute for Advanced Research","keywords":"Chloroform; Chemistry; Biotransformation; Vitamin B12; Chlorine; Fractionation; Cyanocobalamin; Environmental chemistry; Chromatography; Organic chemistry; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004648813,0.0002990536,0.0002936236,0.0002407142,0.0001534548,0.0005687865,0.0003209016,0.0003084633,0.0006033375],"category_scores_gemma":[0.0009278746,0.0002525368,0.0002117874,0.0002591763,0.0003176196,0.0001729603,0.0002832642,0.0004750876,0.0001798038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006046785,"about_ca_system_score_gemma":0.0003071841,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006791457,"about_ca_topic_score_gemma":0.005106631,"domain_scores_codex":[0.9994776,0.0001058773,0.00004246989,0.000129818,0.0001815609,0.00006272286],"domain_scores_gemma":[0.999331,0.0002275185,0.0001335865,0.00008738341,0.0001646526,0.00005592101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001286379,0.000008100075,0.001583673,0.00001365963,0.000005237763,0.00001025253,0.00001733475,0.00006687549,0.9973243,0.00001816917,0.000009402071,0.0008143001],"study_design_scores_gemma":[0.000004054991,0.0001076288,0.01645728,0.000003567736,0.00001002264,0.00005432218,0.00004732993,0.0006585003,0.9822979,0.00002216867,0.0003288276,0.000008289642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959155,0.000309476,0.002642131,0.00004468385,0.000004898459,0.00001708627,0.000383836,0.00005189308,0.0006305156],"genre_scores_gemma":[0.9979123,0.00007614904,0.001266244,0.000027012,8.073258e-7,0.00001402378,0.0003344798,0.00003153466,0.0003374271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006791457,"threshold_uncertainty_score":0.01350385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002574029100281048,"score_gpt":0.2127339733550565,"score_spread":0.2101599442547755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}