{"id":"W4401913876","doi":"10.1128/mbio.01871-24","title":"Identification and characterization of the siderochelin biosynthetic gene cluster <i>via</i> coculture","year":2024,"lang":"en","type":"article","venue":"mBio","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Siderophore; Gene cluster; Nonribosomal peptide; Biology; Gene; Actinobacteria; Bacteria; Microbiology; Virulence factor; Virulence; Biosynthesis; Computational biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001976666,0.0005442905,0.0004296541,0.0005022225,0.0002274999,0.0004028394,0.0003541646,0.0002903958,0.0005519183],"category_scores_gemma":[0.0003826359,0.0001844294,0.0005732999,0.0005546163,0.0002486956,0.0001997762,0.0006195989,0.0004385591,0.000482403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001871505,"about_ca_system_score_gemma":0.0002632102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001593089,"about_ca_topic_score_gemma":0.001511981,"domain_scores_codex":[0.9996095,0.00005227605,0.00003487002,0.0001220869,0.0001133171,0.00006785966],"domain_scores_gemma":[0.9996356,0.00006841057,0.00008204932,0.00006032665,0.00007721748,0.00007631517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003179651,0.0000150022,0.0007683793,0.000014841,0.000003343911,0.00004292556,0.000009678604,0.00001549852,0.9980931,0.000009331839,0.00001304399,0.0009831627],"study_design_scores_gemma":[0.000006126268,0.0003013743,0.01875859,0.000005388952,0.00003031047,0.0003637713,0.00009024027,0.0008384588,0.9779828,0.00002457341,0.00158816,0.00001021833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870061,0.0005073348,0.00954067,0.00008081623,0.00003968273,0.0001567535,0.0010706,0.0001272685,0.001470744],"genre_scores_gemma":[0.9756097,0.0004576533,0.0170736,0.00009233521,0.00003119925,0.0002004243,0.004456835,0.00009510701,0.001983131],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001593089,"threshold_uncertainty_score":0.003167689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006785135809057155,"score_gpt":0.2165598662281991,"score_spread":0.2097747304191419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}