{"id":"W4402039203","doi":"10.1016/j.actbio.2024.08.046","title":"Trabecular meshwork cell differentiation in response to collagen and TGFβ-2 spatial interactions","year":2024,"lang":"en","type":"article","venue":"Acta Biomaterialia","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; University of Glasgow; Engineering and Physical Sciences Research Council; Science Foundation Ireland; Canada Foundation for Innovation","keywords":"Trabecular meshwork; Mesenchymal stem cell; Myofibroblast; Extracellular matrix; Cell biology; Glaucoma; Phenotype; Pathology; Biology; Fibrosis; Medicine; Neuroscience; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001009466,0.0001113784,0.0001057496,0.0001169793,0.0001283813,0.0002537119,0.00005878143,0.0001738252,0.0006325208],"category_scores_gemma":[0.0001191593,0.0001036134,0.0001005344,0.0001423832,0.0001483833,0.0001091627,0.0001160018,0.000274035,0.0001547947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001868934,"about_ca_system_score_gemma":0.0002144591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001796719,"about_ca_topic_score_gemma":0.003495286,"domain_scores_codex":[0.9998925,0.00001527884,0.00001030517,0.00001853948,0.00004100303,0.00002239321],"domain_scores_gemma":[0.9999182,0.00001882797,0.00001958147,0.000008508443,0.00001650569,0.00001848241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008492247,0.00002127219,0.000752426,0.00003109719,0.000002594747,0.00008302838,0.00006851048,0.000127501,0.9973314,0.00009381326,0.00004537153,0.0013581],"study_design_scores_gemma":[0.0000597902,0.0008755826,0.0439375,0.00003597778,0.00002952854,0.0006685328,0.0004713058,0.004979779,0.9413374,0.0001919683,0.007396883,0.00001571228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954948,0.0005530223,0.001454514,0.00003883488,0.00001954814,0.00002274538,0.0001261855,0.00001866737,0.002271565],"genre_scores_gemma":[0.9962901,0.000479587,0.001470759,0.00004167128,0.000007826337,0.00003872037,0.0001667969,0.000006393715,0.001498173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001796719,"threshold_uncertainty_score":0.003572524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007785896729155025,"score_gpt":0.2636048094036195,"score_spread":0.2558189126744645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}