{"id":"W4402044389","doi":"10.1016/j.carbpol.2024.122686","title":"Dissecting the Enterococcal Polysaccharide Antigen (EPA) structure to explore innate immune evasion and phage specificity","year":2024,"lang":"en","type":"article","venue":"Carbohydrate Polymers","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Directorate for Biological Sciences; Université de Lille; Uniformed Services University of the Health Sciences; University of Sheffield; University of Texas at Dallas","keywords":"Rhamnose; Microbiology; Innate immune system; Biology; Enterococcus faecalis; Immune system; Glycan; Glycoconjugate; Polysaccharide; Pathogen; Bacteria; Biochemistry; Immunology; Glycoprotein; Genetics; Staphylococcus aureus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009108028,0.0002002358,0.0001411254,0.00006036782,0.0002886071,0.00023862,0.000212509,0.00006146586,0.00198902],"category_scores_gemma":[0.00001546819,0.000142089,0.00008148317,0.0003506131,0.0001250208,0.0002922068,0.0002948204,0.0002754731,0.0001405995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001078685,"about_ca_system_score_gemma":0.000006981607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001189429,"about_ca_topic_score_gemma":0.0001977115,"domain_scores_codex":[0.998887,0.00003866868,0.0002120897,0.0004087777,0.0001244502,0.000328996],"domain_scores_gemma":[0.9995394,0.00003952322,0.00003836058,0.0002441615,0.000006517735,0.000132033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001522699,0.0000087164,0.0003645469,0.000006419413,0.00002662204,0.00002060664,0.002969645,0.00003560488,0.9855089,0.00001722367,0.0001318653,0.01089459],"study_design_scores_gemma":[0.0001666881,0.00008159833,0.06456231,0.0001364277,0.00006634186,0.00007498442,0.002180639,0.001227724,0.9159274,0.00009488292,0.01503146,0.0004496077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954925,0.0007974604,0.0000873697,0.001065287,0.00136124,0.0002381801,0.00003474762,0.00006248472,0.0008607598],"genre_scores_gemma":[0.9985015,0.00008000075,0.00003137168,0.000209117,0.0001642228,0.00001180413,0.000008854155,0.0000294735,0.0009636761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06958159,"threshold_uncertainty_score":0.9989233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01636467480205397,"score_gpt":0.2563505369579854,"score_spread":0.2399858621559314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}