{"id":"W4402070392","doi":"10.1016/s2352-4642(24)00167-6","title":"Late effects after allogeneic haematopoietic cell transplantation in children and adolescents with non-malignant disorders: a retrospective cohort study","year":2024,"lang":"en","type":"article","venue":"The Lancet Child & Adolescent Health","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; Office of Naval Research; Pharmacyclics; Takeda Oncology; Health Resources and Services Administration; Legend Biotech; Istituto Nazionale Tumori IRCCS \"Fondazione G. Pascale\"; MorphoSys; Swedish Orphan Biovitrum; Vertex Pharmaceuticals; Omeros Corporation; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; Kiadis Pharma; bluebird bio; Jazz Pharmaceuticals; StemCyte; Actinium Pharmaceuticals; CareDx; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; CSL Behring; BeiGene; HistoGenetics; Atara Biotherapeutics; National Cancer Institute; Gilead Sciences; Sanofi; GlaxoSmithKline; Gateway for Cancer Research; Mallinckrodt Pharmaceuticals; Astellas Pharma US; Amgen","keywords":"Medicine; Retrospective cohort study; Oncology; Transplantation; Haematopoiesis; Cohort; Cohort study; Hematopoietic cell; Hematopoietic stem cell transplantation; Internal medicine; Stem cell; Immunology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007624523,0.0003954954,0.0006173907,0.0007647834,0.0006667929,0.00122703,0.0007143632,0.001017376,0.001880369],"category_scores_gemma":[0.002797461,0.0006524676,0.00139371,0.00167648,0.0003952908,0.001019541,0.0007761513,0.002244281,0.0003150573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006871979,"about_ca_system_score_gemma":0.0008967355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01411208,"about_ca_topic_score_gemma":0.01553527,"domain_scores_codex":[0.9992618,0.0001097709,0.00008669027,0.0001885065,0.00008841906,0.0002648069],"domain_scores_gemma":[0.9974563,0.0003173169,0.001292055,0.0002537366,0.0001757217,0.0005048909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001359432,0.00003351814,0.9988612,0.00001450924,0.0001190271,0.0001723553,0.00008357783,0.00001423819,0.00006975135,0.00002318892,0.0001052918,0.0003674885],"study_design_scores_gemma":[0.00000951279,0.00012448,0.9984835,0.00001799173,0.00008319297,0.0005998346,0.0003425947,0.00003064573,0.00002949986,0.00002115426,0.000251674,0.000005992328],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975914,0.001139245,0.00006586962,0.00007653021,0.0000202982,0.00001080965,0.0008009684,0.000002595337,0.0002922514],"genre_scores_gemma":[0.9980204,0.0006516392,0.00005085477,0.00007550685,0.00002612796,0.00001604212,0.000880764,0.000005135053,0.0002735242],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01411208,"threshold_uncertainty_score":0.0280599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005267790921373272,"score_gpt":0.2485074017056302,"score_spread":0.2432396107842569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}